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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A8T1VDY5",
"id": "A0A8T1VDY5_9STRA",
"source_organism": {
"taxId": "221518",
"scientificName": "Phytophthora pseudosyringae",
"fullName": "Phytophthora pseudosyringae"
},
"name": "Endonuclease III homolog",
"description": [
"Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines"
],
"length": 351,
"sequence": "MRSILARPSLRRIASSSLTDPVATTLGGMRLRSSGPVDGDTSLEKKAMAMKLEGGHPPSPLRPARRRHSGKTEDENVGIKREKAERTEEETLRTPKKKAKKAAVKKERVPRKEPEGWKEILRGIEEMRAKKDAEVDKYGCEVFFDESFPPQVCRFHVLIAAMMSSQTKDPVNAAAMGRLIKRGLTVESMLEIDQQELAQLIRPVGFFNHKAKYIKQTASILTKQAEAEGKEDVDIPNTYEGLIALPGVGPKMATLVMNCAWNNTVGICVDTHVHRISNRLKWVKTWNKNNPKSQNPEKTRTELEDWLPKEHWGPINPLLVGFGQTICLPRGPKCNDCKIRGSCPSANSSAI",
"proteome": "UP000694044",
"gene": "NTHL1_3",
"go_terms": [
{
"identifier": "GO:0006284",
"name": "base-excision repair",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0003677",
"name": "DNA binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0003906",
"name": "DNA-(apurinic or apyrimidinic site) endonuclease activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0019104",
"name": "DNA N-glycosylase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006281",
"name": "DNA repair",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0006285",
"name": "base-excision repair, AP site formation",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0005634",
"name": "nucleus",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "ddd5072a1223698000690500e0e6a81f15308649",
"counters": {
"domain_architectures": 16761,
"entries": 9,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cdd": 1,
"pfam": 2,
"smart": 1,
"panther": 1,
"hamap": 1,
"interpro": 3
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 16761
}
}
}