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{
    "metadata": {
        "accession": "A0A8M1GAF7",
        "id": "A0A8M1GAF7_URSMA",
        "source_organism": {
            "taxId": "29073",
            "scientificName": "Ursus maritimus",
            "fullName": "Ursus maritimus (Polar bear)"
        },
        "name": "Ceruloplasmin",
        "description": [
            "Multifunctional blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Copper ions provide a large number of enzymatic activites. Oxidizes highly toxic ferrous ions to the ferric state for further incorporation onto apo-transferrins, catalyzes Cu(+) oxidation and promotes the oxidation of biogenic amines such as norepinephrin and serotonin. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. Has glutathione peroxidase-like activity, can remove both hydrogen peroxide and lipid hydroperoxide in the presence of thiols. Also shows NO-oxidase and NO2 synthase activities that determine endocrine NO homeostasis"
        ],
        "length": 1053,
        "sequence": "MQLYPQREHSDIYLQNGPDRIGRLYKKALYLQYTDKTFTTVIEKPTWLGFLGPIIKAETGDEVYVHLKNFASRPYTFHPHGITYHKEHEGAIYPDNTTDFYKADDKVYPGEQYTYVLDANQDQSPGEEDSNCVTRIYHSHIDAPKDIASGLIGPLIICKKDSLDYEKEKNIDQEFVVMFSVVDENLSWYLDDNIKTYCSEPEKVDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVRWYLFGMGNEVDVHAAFFHGQVLTNKNYRIDTVNLFPATLFEAFMVAQNPGEWLLSCQNLNHLKAGLQAFFQVQDCNKTSSEDNIRGKHVRHYYIAAEEIIWNYAPSGIDVFTKESLTAPGSASEVFFKQGTTRIGGSYKKLVYREYTDASFTNQKKRGPEEEHLGLLGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRVSKNNEGTYYTSHHNPLSEGVPPPSASHVAPKQTFTYEWTVPKEVGPTYKDPVCLSKMYYSAVDPTKDIFTGLIGPMKICRKGSLRANGRPKDVNKEFYLFPTVFDENESLLLDDNIRMFTTAPHLVNKEDEDFQESNKMHSMNGFMYGNQPGLNMCRGDSVMWYLFSAGNEADVHGIYFTGNTYLSKGERRDTANLFPQTSVTLLMEPDTEGTFDVECLTTDHYTGGMKQKYTVNKCRRMSDDPSVHLPERTYYIAAVEVEWDYSPSREWERELHRLQEQNVSNPFLDKEEFYIGSKYKKVVYRQYTDSTFRVPAERKAEGEHLGILGPQLHADVGDIVKIIFKNMATRPYSIHAHGVKTESSTVTPTLPGEIHTYIWKIPERSGAGIEDSACIPWAYYSTVDQVKDLYSGLIGPLIVCRRSYTKVFNPITKLEFSLLFFVFDENESWYIDDNIKTYSEHPEKVNKDDEEFIESNKMHAINGRMFGNLQGLTMHVGDEVSWYLMGMGNEIDLHSVHFHGHSFRYQHRGIYSSDVFDVFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTVLPNKASSQTHKRIWNVIYSFTVSVIILFQISTREWLGV",
        "proteome": "UP000261680",
        "gene": "LOC103678054",
        "go_terms": [
            {
                "identifier": "GO:0005507",
                "name": "copper ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016491",
                "name": "oxidoreductase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "f6a3edbdd39ce94377a40cff16d31bc54dbe637f",
        "counters": {
            "domain_architectures": 440,
            "entries": 20,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "pfam": 3,
                "cdd": 4,
                "panther": 1,
                "prosite": 2,
                "interpro": 8
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 440
        }
    }
}