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{
    "metadata": {
        "accession": "A0A8D2KE93",
        "id": "A0A8D2KE93_UROPR",
        "source_organism": {
            "taxId": "9999",
            "scientificName": "Urocitellus parryii",
            "fullName": "Urocitellus parryii (Arctic ground squirrel)"
        },
        "name": "DIS3-like exonuclease 2",
        "description": [
            "3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation"
        ],
        "length": 890,
        "sequence": "MSHPDYRLNLRPLGTPRGVSSVIGPHGFGASPGDKKSKNKSTRGKKRSIFETYMSKEAVSEGLKRGALIQGVLRINPKKFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEQWKVIKPESNDKETEAAYESDLPEELCGNHLPQQALKGYNDSPDVIIEAQFGDSDSEEGHGDTQNVLVDGVEKLSVRTQDKGKEDANAPVTKDESTSMSQDTKALSEKSLQKSAKVVYILEKKHSRAATGILKLLADKNSELFRKYALFSPSDHRVPRIYVPLKDCPQDFVTRPKDYANTLFICRIVDWKEDSNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQSLPWTIPPEELSKRRDLRKDCIFTIDPSTARDLDDALSCRPLADGTFEVGVHIADVSYFVPEGSHLDKVAADRATSVYLVQKVVPMLPRLLCEELCSLNPMTDKLTFSVIWTLTPEGKILKEWFGRTIIRSCTKLSYEHAQSMIESPSEKIPEEELPPISPEHSSEEVHQAVLNLHRIAKQLRQQRFVDGALRLDQLKLAFTLDSETGLPQGCHIYEYRDSNKLVEEFMLLANMAVAHKVYRAFPEQALLRRHPPPQMKMLNDLVEFCDQMGLSMDASSAGALNKSLTKIFGDDKYSLARKEVLTNMYSRPMQMALYFCSGVLQDQAQFRHYALNVPLYTHFTSPIRRFADVMVHRLLAAALGYREQPEVEPHALQKQADHCNDRRMASKRVQELSASLFFAVLVKESGPLESEAMVMGVLNQAFDVLVLRYGVQKRIYCNALALRSYHFQKVGKKPELTLIWEPKDPEQEPARQVRAPHIPSAPQVAVGPLLPPRCPLCPHLPPPSLALQAPGGASGLHAKAPATPRAQVAS",
        "proteome": "UP000694417",
        "gene": "DIS3L2",
        "go_terms": [
            {
                "identifier": "GO:0003723",
                "name": "RNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0004540",
                "name": "RNA nuclease activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0000175",
                "name": "3'-5'-RNA exonuclease activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "85907db5b452707f679a7c0e15d34ba86372851e",
        "counters": {
            "domain_architectures": 1246,
            "entries": 20,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 3,
                "ssf": 1,
                "pfam": 4,
                "smart": 1,
                "hamap": 1,
                "panther": 1,
                "prosite": 1,
                "interpro": 8
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1246
        }
    }
}