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{
    "metadata": {
        "accession": "A0A8D2IKE1",
        "id": "A0A8D2IKE1_UROPR",
        "source_organism": {
            "taxId": "9999",
            "scientificName": "Urocitellus parryii",
            "fullName": "Urocitellus parryii (Arctic ground squirrel)"
        },
        "name": "Cell cycle checkpoint protein RAD17",
        "description": [
            "Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the 9-1-1 (RAD1-RAD9-HUS1) complex and RHNO1 onto chromatin, and in CHEK1 activation. Involved in homologous recombination by mediating recruitment of the MRN complex to DNA damage sites. May also serve as a sensor of DNA replication progression"
        ],
        "length": 678,
        "sequence": "MSKTFLRPKVSSTKVIDWVDPAFDDFSENTVVSTAAPLGVNNSSHRRKYVPPALESSRFPARKRGKLFSSEQIFGLENSKEYLSENEPWVDKYKPETQHELAVHKKKIEEVETWLKAEVLERQSKQGGSILLITGPPGCGKTTTIKILSKEHGIQVQEWINPVLPDFQKDDFKDIFNFESNFHSFPYQSQIAVFREFLLRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVQIGRCPLIFIISDSASGDNNHRLLFPKEIQEECSIANISFNPVAPTIMMKFLNRIVTIEANKNGGKIIVPNKTSLELLCQGCSGDIRSAINSLQFSSSKGESNLWPRKKGVSLKSDAALSKSKRVKKPDRVIENQEIQAIGGKDASLFLFRALGKILYCKRAPLTELDSPRLPSHLSEHERDTLLIQPEEVVEMSHMPGELFNLYLHQNYIDFFMEVDDLVRASEFLSFADVLSGDWNTRSLLREYSTSVATRGVMHSNKARGFAHCQGGGSSFRPLHKPQWFLIFKKYRENCMAAKALFSDFCLPALCLQTQLLPYLALLTIPMRNQAQISFIQDIGRLPLKQHFRRLKMEALMDREHGLIDPDTGNEAQLNGAQTTEENQGEPTQTAEPEILPLSQNSGSELPASQPQPFSSQVDMEEEDIIIEDYESDGT",
        "proteome": "UP000694417",
        "gene": "RAD17",
        "go_terms": [
            {
                "identifier": "GO:0003689",
                "name": "DNA clamp loader activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0000077",
                "name": "DNA damage checkpoint signaling",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0006281",
                "name": "DNA repair",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005634",
                "name": "nucleus",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0031389",
                "name": "Rad17 RFC-like complex",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "4b4062e3f9ca81c610feb7a18e9726e715fb5a9b",
        "counters": {
            "domain_architectures": 2806,
            "entries": 9,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "pfam": 1,
                "cathgene3d": 1,
                "ssf": 1,
                "cdd": 1,
                "ncbifam": 1,
                "panther": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 2806
        }
    }
}