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{
    "metadata": {
        "accession": "A0A8C6S302",
        "id": "A0A8C6S302_NANGA",
        "source_organism": {
            "taxId": "1026970",
            "scientificName": "Nannospalax galili",
            "fullName": "Nannospalax galili (Northern Israeli blind subterranean mole rat)"
        },
        "name": "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein",
        "description": [
            "Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils"
        ],
        "length": 1643,
        "sequence": "MEAPDSSGDPGGDGTQPDARVPGSGQCVAARESERQLRLRLCVLNEILGTKRDYVGTLRFLQSAFLQRIRQNVADSVEKGLTEENVKILFSNIEDILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKVPAARAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAVQSALQAMKTVCSNINETKRQMEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGMLLKISAGNIQERAFFLFDNLLVYCKRKSRVTGSKKSTKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDALIREREQRESLKLGMERDAYVMIAEKGEKLYHMMMNRKVNLIKDRRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGINLGQALLENGIIHHVSDKHQFKNEQVMYRFRYDDGTYKARSELEDIMSKGVRLYCRLHSLYTPVIKDRDYHLKTYKSVLPGSKLVDWLLTQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFKDESQYFRFHADEEMEGTSSKNKQLRNDFKLVENILAKRLLIPPQEEDYGFELEEKNKAVVVKLVQRGSLAEMAGLQMGRKVYSINEDLVFLRPFSEVETILNQSFCSRRPLRLLVATKARETIKVPDHPEALSFQIRGAAPPCIFAVGRGSEAVTAGLCAGQCILKVNGNSVANDGALEVLEHFQAFRSRREEALGLYQWVYHSHEDAQQARASQGAPDEDPQEDDQPDSALPLLSLGPQLSLREDSAVVSLMVDNVHLEHGVVYEYVSTAGAKCHVLEKIVEPRGCFRLAAKILEAFAADDSIFVQNCGRLMAMSSAIVTMPHYEFRNICDTKLENIGQRIAHYQEFAVHLKNRVSPPFKQAPLEPHPLCGLDFCPTNCHVNLMEVSYPKTTPSVGRSFSIRFGRKPSLIGLDPEQGHLNPMSYTQHCITTMAAPSWKCLPAADGDPQGQGLSDSSFGPASGTLSQQDRGLSFLLRQEDREIQDGYLQLFTKLDVALKEMKQYVTQINRLLSTITEPTSAAPCDPSLAEETSSSPLVSEESEADRTDHGGIKKVCFKVSEDEQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNSSYLGSDEMGSGDELPCDMRIPSDKQDKLHGCLEHLFNQVDSIHTLLKGPVMSRAFEETRHFPMEHNWQEFKQKEECTVRGRSLIQISIQEDPWNLPSSIRTLVDNIQRYVEDGKNQLLLALLKCTDTELQLRRDAIFCQALVAAVCTFSEQLQAALSYRYNNNGEYEDSSRDASRKWLEQVAAIGALLHWQSLLAPASVKEEQIMLEDIWVALSELDSVTFSFKQLDENSVANTNIFYHIEGSRQALKVVFYLDSFHFSRLPSRLEGGASLRLHTVLFTKALEGVEGPPPGSQAVEELQQEINSQSLEKVQQYYRKLRAFYLERSNLPTDTNSTAVKIDQLIRPINALDELCRLMKSLVHPKPGTTGNLGAGLIPVSSELCYRLGACQITMCGTGMQRSTLSVSLEQAAILARSHGLLPKCVMQATDIMRKQGPRVEILAKNLRIKDPMPQGAPRLYRLCQPPVDGDL",
        "proteome": "UP000694381",
        "gene": "Prex1",
        "go_terms": [
            {
                "identifier": "GO:0005085",
                "name": "guanyl-nucleotide exchange factor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0035556",
                "name": "intracellular signal transduction",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "acc90197b10e90cd7e7b8cdea4a3498807956ec7",
        "counters": {
            "domain_architectures": 1338,
            "entries": 33,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 6,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 4,
                "ssf": 4,
                "profile": 3,
                "cdd": 3,
                "pfam": 3,
                "smart": 3,
                "panther": 1,
                "prosite": 1,
                "interpro": 11
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1338
        }
    }
}