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{
    "metadata": {
        "accession": "A0A8C6A251",
        "id": "A0A8C6A251_MARMA",
        "source_organism": {
            "taxId": "9994",
            "scientificName": "Marmota marmota marmota",
            "fullName": "Marmota marmota marmota (Alpine marmot)"
        },
        "name": "Exopolyphosphatase PRUNE1",
        "description": [
            "Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration and differentiation, and acts as a negative regulator of NME1. Plays a role in the regulation of neurogenesis. Involved in the regulation of microtubule polymerization"
        ],
        "length": 422,
        "sequence": "MVSALALAFYLTKTNEAEEVFIPVLNIKRSELPLRGDNVFFLQKIQIPETILIFRDEIDLHALHQAGQLTLILVDHHVLPKSDAALEEAIVEVLDHRPIEQKHCPLCHVSVELVGSCATLVAERILQGAPEILDRQTAALLHGTIILDCVNMDIKIGKATPKDNEYVEKLEALFPDLPKRNDIFDFLQKAKFDVSGLTTEQILRKDQKTIHRQGTKVAISAVYMDLEAFLQRPNLLADLSAFCQAHSYDALVAMTIFFNAHNEPVRQLAIFCPHVALRMMICEVLERSHSPPLKLTPVPNTHPNLQAYLQGNTQVSRKKLLPLLQEALSTYFDSTKIPSGQPETVGVSREQVDKDLDRAGHALISGLSQDEEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTTASLSNK",
        "proteome": "UP000694407",
        "gene": "PRUNE1",
        "go_terms": [
            {
                "identifier": "GO:0016462",
                "name": "pyrophosphatase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005737",
                "name": "cytoplasm",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "4666e48c38cf2b003f8ebbefc2ecf2e07bf34761",
        "counters": {
            "domain_architectures": 1442,
            "entries": 9,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 0,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "ssf": 1,
                "smart": 1,
                "panther": 1,
                "pfam": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1442
        }
    }
}