GET /api/protein/UniProt/A0A8C3M6E6/?format=api
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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A8C3M6E6",
"id": "A0A8C3M6E6_GEOPR",
"source_organism": {
"taxId": "87175",
"scientificName": "Geospiza parvula",
"fullName": "Geospiza parvula (Small tree-finch)"
},
"name": "Protein VAC14 homolog",
"description": [
"Scaffold protein component of the PI(3,5)P2 regulatory complex which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Pentamerizes into a star-shaped structure and nucleates the assembly of the complex. The pentamer binds a single copy each of PIKFYVE and FIG4 and coordinates both PIKfyve kinase activity and FIG4 phosphatase activity, being required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes"
],
"length": 779,
"sequence": "MNAERDLSPLTPGVVRALTDKLYEKRKVAALEIEKLVREFVAQNNTSQIKHVIQILSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNQFDLVGFIPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVALGEFLKEIKKNPSSVKFAEMANILVIHCQAADDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVCNQSLMKLVIPEDDEMDEAKPSMTIPAEPTSEESLSRPEAVTAGSLDASGDSSNSGVFTVTSCERIQVTLNLDGIVQVLDYHLSDTSIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLRTLSDESDEVILKDLELLAEIASSPAGQTEEGHGPSDGSDVRPGPVELHVPARPGQLSSSSTKGLECSPSTPTMNSYFYKFMINLLKRFSSERKLLEARGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHTLNTILLTSSELFQLRNQLKDLKTPESRNLFCCLYRSWCHNPVTTVSLCFLTQNYKHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPELMQTTDNSKPSTSFKRTAASNIDYTELLQHFEKVQNKHLEARHQRAGRAEQLDRRVVL",
"proteome": "UP000694382",
"gene": "VAC14",
"go_terms": [
{
"identifier": "GO:0006661",
"name": "phosphatidylinositol biosynthetic process",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0070772",
"name": "PAS complex",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "3ef46bdb6099f1f76d6b7728ccc114eda7db1a5a",
"counters": {
"domain_architectures": 4175,
"entries": 9,
"isoforms": 0,
"proteomes": 1,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"ssf": 1,
"pfam": 2,
"panther": 1,
"interpro": 4
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 4175
}
}
}