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{
    "metadata": {
        "accession": "A0A8C3F6D3",
        "id": "A0A8C3F6D3_CHRPI",
        "source_organism": {
            "taxId": "8478",
            "scientificName": "Chrysemys picta bellii",
            "fullName": "Chrysemys picta bellii (Western painted turtle)"
        },
        "name": "Pseudouridylate synthase TRUB1",
        "description": [
            "Pseudouridine synthase that catalyzes pseudouridylation of mRNAs and tRNAs. Mediates pseudouridylation of mRNAs with the consensus sequence 5'-GUUCNANNC-3', harboring a stem-loop structure. Constitutes the major pseudouridine synthase acting on mRNAs. Also catalyzes pseudouridylation of some tRNAs, including synthesis of pseudouridine(55) from uracil-55, in the psi GC loop of a subset of tRNAs. Promotes the processing of pri-let-7 microRNAs (pri-miRNAs) independently of its RNA pseudouridylate synthase activity. Acts by binding to the stem-loop structure on pri-let-7, preventing LIN28-binding (LIN28A and/or LIN28B), thereby enhancing the interaction between pri-let-7 and the microprocessor DGCR8, which mediates miRNA maturation"
        ],
        "length": 289,
        "sequence": "MAEEVHGKLGHVMANPAAKLLSLSGLFAVYKPKGPTSANVLNQLKEKLLAEAGIQKCVRKRKKQILKIGHGGTLDSAAAGVLVVGIGKGTKMLGNILAGSKKYLAIGELGKATDTLDATGKVTEEKPYDQITKEDLERVLQKFTGDIMQVPPLYSALKRDGQRLSSLMKKGEAVEAKPARPVTVYSLSLQNFQSPLFTLDVECGGGFYVRSLVSDIGKELSSCANVQELTRTKQGPFTLEEHALHEDKWTIDEIAQSLEHCMSFLAVEPSLKKLKTEHSEESTVNCEDK",
        "proteome": "UP000694380",
        "gene": "TRUB1",
        "go_terms": [
            {
                "identifier": "GO:0003723",
                "name": "RNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0009982",
                "name": "pseudouridine synthase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0001522",
                "name": "pseudouridine synthesis",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0009451",
                "name": "RNA modification",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0006396",
                "name": "RNA processing",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "28a6c0c889cc202e14ae965a0574b1a1c3b7da3c",
        "counters": {
            "domain_architectures": 6466,
            "entries": 9,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "pfam": 1,
                "panther": 1,
                "hamap": 1,
                "ncbifam": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 6466
        }
    }
}