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{
    "metadata": {
        "accession": "A0A8C2MMI3",
        "id": "A0A8C2MMI3_CRIGR",
        "source_organism": {
            "taxId": "10029",
            "scientificName": "Cricetulus griseus",
            "fullName": "Cricetulus griseus (Chinese hamster)"
        },
        "name": "Adhesion G-protein coupled receptor D1",
        "description": [
            "Adhesion G-protein coupled receptor (aGPCR) for androgen hormone 5alpha-dihydrotestosterone (5alpha-DHT), also named 17beta-hydroxy-5alpha-androstan-3-one, the most potent hormone among androgens. Also activated by methenolone drug. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRD1 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Acts as a 5alpha-DHT receptor in muscle cells, thereby increasing intracellular cyclic AMP (cAMP) levels and enhancing muscle strength"
        ],
        "length": 903,
        "sequence": "MRDLPTLPCHWVCLLWSFCSFQVCGTQPRAQEHPGFAVLASASHYWPLENVDGILELQDTTGALRTHNLTVPPSHNATFVFTNDSAYSNFSATVDIMEGKVNKGIYLKEEKGVTFLYYGSYKSSCISNPAQCGPEGVTFSFFWKTQEEQPRPAPYAYGGQVISDGFKVCSSGGKGSVELYTRDNSMTWKATFNPPGPYWTHVLFTWKSKEGLKVYVNGTLSTSDPSGKVSHTYGEPHVNLVIGSEQDQTKRYENGAFDEFIIWERALTPDEIKMYFTAAIGKHSLLSSTPPAMPTAHSMVPTDAYHPIITNLTEERKCFQRPETVLRYLQNVSLSLPNKSLSEETALNLTQTFLRTVGEVLLLPSWTHVSEDNTMTLGLVDTIDTVMGHISANLQSREPHITLTGSSSMADFFVAKVLPPALSAPHYRFPAHGHSYIEIPREALHGKAWTTIVGLLYHSMHYYLNNIPPASTKIPEAVNCRDCLLSVASHLISLEVSPPPTLSQNLSGSPLITVHLRHKLTHKQYVDATNESNDLFLYCAFLNFSSGEGIWSSQGCALREGNLTHSVCHCTHLTNFAILMQVVPLQLTRGHQVALSSISYVGCSLSVLCLAATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRVEPGTVPCQVLAILLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHLYYYGIGWGCPLLICIISISSSMDSYGTNDSCWLSLGSGAIWAFVGPALLVIVVNIVILVAVTRVISHVSTDNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVSDRALVFQYMFAVLNSLQGLFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSARTTNTKPFSSDIVNGTRPGTASTKLSPWDKSSHSAHRVDLSAV",
        "proteome": "UP001108280",
        "gene": "Adgrd1",
        "go_terms": [
            {
                "identifier": "GO:0004930",
                "name": "G protein-coupled receptor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0007186",
                "name": "G protein-coupled receptor signaling pathway",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0016020",
                "name": "membrane",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0004888",
                "name": "transmembrane signaling receptor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0007166",
                "name": "cell surface receptor signaling pathway",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "e6ecd940feaf4815481406bfc2e7db50b9700357",
        "counters": {
            "domain_architectures": 1235,
            "entries": 22,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 1,
                "profile": 3,
                "cathgene3d": 3,
                "pfam": 3,
                "smart": 1,
                "panther": 1,
                "prints": 1,
                "prosite": 1,
                "interpro": 8
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1235
        }
    }
}