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{
    "metadata": {
        "accession": "A0A8B8T8P4",
        "id": "A0A8B8T8P4_CAMFR",
        "source_organism": {
            "taxId": "419612",
            "scientificName": "Camelus ferus",
            "fullName": "Camelus ferus (Wild bactrian camel)"
        },
        "name": "Serine/threonine-protein kinase MRCK beta",
        "description": [
            "Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A. In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation"
        ],
        "length": 1712,
        "sequence": "MSAKVRLKKLEQLLLDGPWRNESSLSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITTLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRNVEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSLKSIMQSSTLTKDEGVQRDLENSLQVEAYERRIRRLEQERLELSRKLQESTQTVQSLHGSARALGSSARDKEIKKLNEEIERLKNKIADSNRLERQLEDTVTLRQEHEDSTLRLKGLEKQYRVVRQEKEEFHKQLIEASERLKSQARELKDAHQQRKLALQEFSELNERMAELRSQKQKLSRQLRDKEEEVEVAMQKIDSLRQEARRSDKCRKELEAQLEDAVAEASKERTLREHSENFSKQIESELEALKMKQGGRGPGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLALQKEVLVLRDKLEKSKRERLSEVEEAVGTLRDKHERERAMLFEENKKVTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELETLRSSSLGSRTLDPLWKVRRSQKLDMSARLELQSALEAEIRAKQLVQEELRKVKDSNLAFESKLKDSEAKNRELLEEMEILKKKMEEKFRADTGLKLPDFQDSIFEYFNAAPLAHDLTFRTSSTSEQETQAPKPEASPPVSGAASMDQQEDTARAPQRPPPVPLPATQALALAGPKPKAHQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFACHVSCKDSAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGYVKVPKPTGVKKGWQRAYAVVCDCKLFLYDLPEGKSTQPGVVASQVLDLRDDEFSVSSVLASDVIHASRRDIPCIFRVTASLLDTPSRTSSLLILTENENEKRKWVGILEGLQSILHKNRLRSQVVHIPQEAYDSSLPLIKAVLTAAIVDGERVAVGLEEGLYTIEVTRDVIVRVADYKKVYQIELAPKEKVAVLLCGRNHHVHLCPWSAFDGVESNIDVKLPETKGCQLIATGTLKKGSPTCLFVAVKRLVLCYEVQRTKPFHRKLSEAVAPGTVQWMAVLKDKLCVGYPSGFSLLSAQGDGQALNLVNPNDPSLTFLSQQSFDALCAVELKSEEYLLCFSHMGLYVDPQGRRSRTQELMWPAAPVACSCSSSHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNSEGSLNLLNCEPPRLIYFKSKSAGAILSVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAVPPSQEERPGPAPASLPRQPPPRNKPYISWPSSGGSESGVAVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPLEGLEQPAYDA",
        "proteome": "UP000694856",
        "gene": "CDC42BPB",
        "go_terms": [
            {
                "identifier": "GO:0004674",
                "name": "protein serine/threonine kinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0004672",
                "name": "protein kinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006468",
                "name": "protein phosphorylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "b0e583d90c33df2b089e551aa86c0d2697d5cf68",
        "counters": {
            "domain_architectures": 483,
            "entries": 52,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 8,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cdd": 4,
                "cathgene3d": 5,
                "ssf": 3,
                "pfam": 6,
                "smart": 6,
                "profile": 6,
                "panther": 1,
                "prosite": 3,
                "prints": 1,
                "interpro": 17
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 483
        }
    }
}