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{
    "metadata": {
        "accession": "A0A7R5L893",
        "id": "A0A7R5L893_9PASS",
        "source_organism": {
            "taxId": "649802",
            "scientificName": "Pipra filicauda",
            "fullName": "Pipra filicauda (Wire-tailed manakin)"
        },
        "name": "PAS domain-containing serine/threonine-protein kinase",
        "description": [
            "Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells; however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate in respiratory regulation"
        ],
        "length": 1158,
        "sequence": "MAAKAFSASEGGLLPSSAGLVLTCLNDSDKLSRSYPWGDKRRKSRLSGLCRLRASLSGEKWSSYCLSSLTARNICSSKTGNSWAQWDSTSLSASIGSSASCSFLHAPAVEESSQHLPAAARNPNKAIFTVDAGTTEILVANDRACKLLGCSSQELIGQKLSHLISKPSQEVWEAVGEEYLETYEWSSVVSGTVMDVRGRLNEKIPVSVWQRQIRSKDTQRCVVVLEPVERLSASVCFRVDGEITSCDLLFAHLHGYPTLEEVVGLHIKDLIPSVQIPPLGKKIPKNLRTQRAAGRSREGNVFPLSLKLQASLLEEDQARVQKDGILQTEGSLPGYQYSATVVVFSTISGLITVQSDGIICGINDSFALMLFGYEKKELLGKNITFLIPGFYNNMERSSECSLPFPPLDDSTGTEERHICIKTNAPHWNKEEFLDGFLDSSSLAASLAHLLSRDEEQKWEQRRKDDKLIHDENKQKSGTGFFSPPSPPEVASTPTNSSRLEDILNTSSYGPVKLPSVVTSNSPGTPTMNEPWPGTALDCRQDFQSHVVTGQASKTNSRCDAEHSSLEQVVVENCLLNDAPAFFAHERNTVYDVCSANKVGHSASAPGAATTSEDVKESDTELNCICSGLEVLGLNTRVKGNSDNSLGVTAALVGACSSDAVDSNMLTETNSTFSAGQGKQLLSGVATEAGSGWLAFQGHLQNSEESSKAFPEAAQTPAETVGHSAGRNPQKGKGGPEELGQLQGQQNMERKVTSTPVKQEGRLNPAAPLIWEILEGSYTGNCCHRDGSQFSILFEVKCAELQDPTVLFCVWVVKDLSQSQKEAVAKTQPLLSSLASSAQSVADLSTNSLGEAIRSTSLFNNSRRAEELGGLRACEGEYTKNYSTLSLIGKGAFGFVWTARSKKDHQEVVVKFIWKERVLEDCWVDDPELGRVTQEIAILLKLQHPSIIKVLDVFENECFFQLVMEKHGSGLDLFTFIDNQPNLDEPLASYIFRQLVSAVGYLHCRNILHRDIKDENIVIAEDFTIKLVDFGSAAYLEPGKLFYTFCGTIEYCSPEVLSGKPYHGPELEMWSLGITLYTLVLGENPFCELEEALAAVLNPPHPVSDGLMDLMAGLLHPIPEERTTLAVLAEDPWLRQPVNLADYTWEEVYISAEPGETTS",
        "proteome": "UP000504627",
        "gene": "PASK",
        "go_terms": [
            {
                "identifier": "GO:0006355",
                "name": "regulation of DNA-templated transcription",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0004672",
                "name": "protein kinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006468",
                "name": "protein phosphorylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "131051ef29cc19e4e5d1718894fd55a365c023ff",
        "counters": {
            "domain_architectures": 245,
            "entries": 24,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ncbifam": 1,
                "profile": 2,
                "smart": 2,
                "cathgene3d": 3,
                "ssf": 2,
                "pfam": 3,
                "cdd": 1,
                "panther": 1,
                "prosite": 2,
                "interpro": 7
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 245
        }
    }
}