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{
    "metadata": {
        "accession": "A0A7K5BPB3",
        "id": "A0A7K5BPB3_MOTAL",
        "source_organism": {
            "taxId": "45807",
            "scientificName": "Motacilla alba",
            "fullName": "Motacilla alba (White wagtail)"
        },
        "name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2",
        "description": [
            "Adapter required to activate the JNK and NF-kappa-B signaling pathways through the specific recognition of 'Lys-63'-linked polyubiquitin chains by its RanBP2-type zinc finger (NZF). Acts as an adapter linking MAP3K7/TAK1 and TRAF6 to 'Lys-63'-linked polyubiquitin chains. The RanBP2-type zinc finger (NZF) specifically recognizes Lys-63'-linked polyubiquitin chains unanchored or anchored to the substrate proteins such as RIPK1/RIP1 and RIPK2: this acts as a scaffold to organize a large signaling complex to promote autophosphorylation of MAP3K7/TAK1, and subsequent activation of I-kappa-B-kinase (IKK) core complex by MAP3K7/TAK1. Also recognizes and binds Lys-63'-linked polyubiquitin chains of heterotypic 'Lys-63'-/'Lys-48'-linked branched ubiquitin chains. Regulates the IL1-mediated translocation of NCOR1 out of the nucleus. Involved in heart development"
        ],
        "length": 698,
        "sequence": "MAQGSQQIDIQVLHDLRQKFPEVPEGVVSRCMLQNNNNLDACCAVLSQESTKYLYGEGDLSFSDDSGIPGLRNHMTSLNLDLQSQNIYHHGREGSRMNGSRTLAHSVSDGHLQTSQSNNELFQQEPQTAPAQVPQGFNVFGMANTVSASNPGQHLGFHLGSKGVSNLSQQTPRFNPIMVTLAPNIQPGRNTPTSLHIHGVPPPVLNSPQGNSIYIRPYITAPSGTARQTQQQPGWASQFNPMHPQQVYQPSQPGPWTTIPTSSTTPHTSSQHSTQPNQQGHQTSHVYMPISSPTTPQAPMIHSSGSSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNSSSKLRSTGPRTSTVPSSLNSQTLSRSQPTVYISASPPNTDEVITRGQPKVYISANATTGDDQLVRNQPTLFISTNPGVSTTARNMSGQVSMGPAFIHHHPPKSRAVGNSTTATSPRVVVTQPNTKYTFKITVSPNKPPAVSPGVVSPTFEPTNLLNLPDHYVEPEGIQHLTDPVLAHVDRISDARKLSMGSDDAAYTQALLVHQKARMERLQRELEVQKKKLDKLKSEVNEMENNLTRRRLKRSNSVSQIPSLEEMQQLRSCNRQLQIDIDCLTKEIDLFQARGPHFNPSAIHNFYDNIGFLGPVPPKPKDQRSIVKTPKTVPDTDEDEGAQWSCTACTFLNHPALNRCEQCEMPRHF",
        "proteome": "UP000532252",
        "gene": "Tab2",
        "go_terms": [
            {
                "identifier": "GO:0043130",
                "name": "ubiquitin binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": true,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "6a1420a2d828932f2dc809150049cfa63156530f",
        "counters": {
            "domain_architectures": 15330,
            "entries": 15,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "smart": 2,
                "profile": 2,
                "cdd": 1,
                "pfam": 1,
                "ssf": 1,
                "panther": 1,
                "prosite": 1,
                "interpro": 4
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 15330
        }
    }
}