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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A7K4PCB4",
"id": "A0A7K4PCB4_MELMO",
"source_organism": {
"taxId": "44397",
"scientificName": "Melospiza melodia",
"fullName": "Melospiza melodia (Song sparrow)"
},
"name": "Nociceptin receptor",
"description": [
"G-protein coupled opioid receptor that functions as a receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin"
],
"length": 368,
"sequence": "MDPLFPARIFEDPDLRKLLNDSSMLNLSFLPSNWFNNSTGDGFLPLSIKITIVVVYSIVCIVGLVGNCSVMYVIVRFTKMKTATNIYIFNLALADTLCLMTLPFQGTDTFLGFWPFGNVLCKIAISIDYYNMFTSTFTLTMMSVDRYIAICHPIKALDIRTPHKAKVVNVCIWALASVFGIPAMVMGSAENENNEIDCLIKLPSPVDYWDPVFGICVFLFSFMIPVLIITICYSLMIRRLKNVRVLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIQIFVLVQCLGAKAESELELAISCFCTALGYANSSLNPVLYAFLDENFKACFKKFCFPTAFRTELQMSNRMCSIAKDVAYACKNSEGTNNPA",
"proteome": "UP000560247",
"gene": "Oprl1",
"go_terms": [
{
"identifier": "GO:0004930",
"name": "G protein-coupled receptor activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0007186",
"name": "G protein-coupled receptor signaling pathway",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0016020",
"name": "membrane",
"category": {
"code": "C",
"name": "cellular_component"
}
},
{
"identifier": "GO:0001626",
"name": "nociceptin receptor activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0004985",
"name": "G protein-coupled opioid receptor activity",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": true,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "587fa3dbe4504dc051049f3cca904dd9ab631b87",
"counters": {
"domain_architectures": 394800,
"entries": 15,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"ssf": 1,
"cathgene3d": 1,
"cdd": 1,
"smart": 1,
"profile": 1,
"pfam": 1,
"panther": 1,
"prosite": 1,
"prints": 3,
"interpro": 4
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 394800
}
}
}