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{
    "metadata": {
        "accession": "A0A7J7ZPE3",
        "id": "A0A7J7ZPE3_PIPKU",
        "source_organism": {
            "taxId": "59472",
            "scientificName": "Pipistrellus kuhlii",
            "fullName": "Pipistrellus kuhlii (Kuhl's pipistrelle)"
        },
        "name": "Bax inhibitor 1",
        "description": [
            "Endoplasmic reticulum (ER)-resident protein that confers cellular protection as an anti-apoptotic protein by limiting multiple stress-inducing pathways surrounding the endoplasmic reticulum and mitochondria. Inhibits the activities of the key sensor for the endoplasmic reticulum unfolded protein response IRE1alpha/ERN1 both directly and by blocking BAX/BAK binding. Modulates ER calcium homeostasis by acting as a calcium-leak channel. Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation"
        ],
        "length": 237,
        "sequence": "MNIFDRKINFDALLKFSHISPSTQQHLKKVYASFALCMFVAAAGAYVHVVTHFVQAGLLSALGSLGLMIWLMTTPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIAINPSIIPTAFMGTAMIFTCFTLSALYARRRSYLFLGGILMSAMSLMLLSSLGNLFFGSIWLFQANLYLGLMVMCGFVLFDTQLIIEKAENGDKDYIWHCVDLFLDFVTLFRKLMMILAMNEKDKKKEKK",
        "proteome": "UP000558488",
        "gene": "mPipKuh1_017496",
        "go_terms": [
            {
                "identifier": "GO:0043066",
                "name": "negative regulation of apoptotic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0016020",
                "name": "membrane",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "82455095b0854e5bcd1644042a3a2dd6ee243050",
        "counters": {
            "domain_architectures": 36348,
            "entries": 6,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cdd": 1,
                "pfam": 1,
                "panther": 1,
                "prosite": 1,
                "interpro": 2
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 36348
        }
    }
}