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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A7J7X5M5",
"id": "A0A7J7X5M5_RHIFE",
"source_organism": {
"taxId": "59479",
"scientificName": "Rhinolophus ferrumequinum",
"fullName": "Rhinolophus ferrumequinum (Greater horseshoe bat)"
},
"name": "Interferon regulatory factor 4",
"description": [
"Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes"
],
"length": 452,
"sequence": "MNLEGGGGRGGEFGMSSVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISDPYKVYRIVPEGAKKGAKQLTLEDPQMTMSHPYTMATPYTSLPAQQVHNYMMPSHDRSWREYVPDQPHPEIPYQCPVTFGPRSHHWQGPACENGCQVTGTFYACAPPESQAPGIPIEPSIRSAEALALSDCRLHICLYYREILVKEVTTASPEGCRISHGHTYDASNLDQVLFPYPEDNGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCGDRPNKLERDQTCKLFDTQQFLSELQAFAHHGRPLPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQNSGHFLRGYDLPEHISSPEDYHRSIRHSSIQE",
"proteome": null,
"gene": "mRhiFer1_006961",
"go_terms": [
{
"identifier": "GO:0000976",
"name": "transcription cis-regulatory region binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0005515",
"name": "protein binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0003700",
"name": "DNA-binding transcription factor activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006355",
"name": "regulation of DNA-templated transcription",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 4,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "621619633400ed25eaadf7725f5360e2921ad3ae",
"counters": {
"domain_architectures": 7057,
"entries": 20,
"isoforms": 0,
"proteomes": 0,
"sets": 3,
"structures": 0,
"taxa": 1,
"dbEntries": {
"smart": 2,
"profile": 1,
"pfam": 2,
"cathgene3d": 2,
"ssf": 2,
"cdd": 1,
"panther": 1,
"prints": 1,
"prosite": 1,
"interpro": 7
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 7057
}
}
}