{"metadata":{"accession":"A0A7J7X5M5","id":"A0A7J7X5M5_RHIFE","source_organism":{"taxId":"59479","scientificName":"Rhinolophus ferrumequinum","fullName":"Rhinolophus ferrumequinum (Greater horseshoe bat)"},"name":"Interferon regulatory factor 4","description":["Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes"],"length":452,"sequence":"MNLEGGGGRGGEFGMSSVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISDPYKVYRIVPEGAKKGAKQLTLEDPQMTMSHPYTMATPYTSLPAQQVHNYMMPSHDRSWREYVPDQPHPEIPYQCPVTFGPRSHHWQGPACENGCQVTGTFYACAPPESQAPGIPIEPSIRSAEALALSDCRLHICLYYREILVKEVTTASPEGCRISHGHTYDASNLDQVLFPYPEDNGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCGDRPNKLERDQTCKLFDTQQFLSELQAFAHHGRPLPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQNSGHFLRGYDLPEHISSPEDYHRSIRHSSIQE","proteome":null,"gene":"mRhiFer1_006961","go_terms":[{"identifier":"GO:0000976","name":"transcription cis-regulatory region binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003700","name":"DNA-binding transcription factor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006355","name":"regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"621619633400ed25eaadf7725f5360e2921ad3ae","counters":{"domain_architectures":7057,"entries":20,"isoforms":0,"proteomes":0,"sets":3,"structures":0,"taxa":1,"dbEntries":{"smart":2,"profile":1,"pfam":2,"cathgene3d":2,"ssf":2,"cdd":1,"panther":1,"prints":1,"prosite":1,"interpro":7},"proteome":0,"taxonomy":1,"similar_proteins":7057}}}