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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A6Q2YJ75",
"id": "A0A6Q2YJ75_ESOLU",
"source_organism": {
"taxId": "8010",
"scientificName": "Esox lucius",
"fullName": "Esox lucius (Northern pike)"
},
"name": "Follistatin-related protein 1",
"description": [
"Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors"
],
"length": 310,
"sequence": "MMLRTLPFLVLLVLALCQAEEVQSKSKVCANVFCGAGRECAVTEKGEPSCLCIESCKPHKRSVCGSNGKTYRNHCELHRDACLTGLKIQVAHDGHCQAKKAEQVAASPVVCYVADRNELRHRVIQWLQNEVVPDGWFVKGSNFTDILLKYFKNYDNGDSQLDSSELLKFIQHNDSNVDLQSYADQESNKLLSLCVDALIELSDENADWKLSFDEFLNCLKPGFNPPEKKCALEDETYDDGSETQVECNRCVCACGNWVCTAMTCTDKTALVEETGEAGQEMTEEEWGLRVAELNKHQETVEKMKVSTKEE",
"proteome": "UP000265140",
"gene": null,
"go_terms": [
{
"identifier": "GO:0005515",
"name": "protein binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0005509",
"name": "calcium ion binding",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 4,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "74d40995f4506b494a617eb31c3cd0d8e3fda7bb",
"counters": {
"domain_architectures": 1227,
"entries": 24,
"isoforms": 0,
"proteomes": 1,
"sets": 6,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 2,
"smart": 2,
"pfam": 4,
"ssf": 3,
"profile": 2,
"cdd": 2,
"panther": 1,
"interpro": 8
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 1227
}
}
}