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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A6P9DNA7",
"id": "A0A6P9DNA7_PANGU",
"source_organism": {
"taxId": "94885",
"scientificName": "Pantherophis guttatus",
"fullName": "Pantherophis guttatus (Corn snake)"
},
"name": "Phosphatidylethanolamine N-methyltransferase",
"description": [
"Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step"
],
"length": 219,
"sequence": "MPLPLDCCGGLNNVDYSKVDLSAMTLLSDYVNVTDPNFIVAVISIAFNPLFWNVVARWEHRTRSLTRIFGSPYVACYFLGVVIILLNFLRTHCFGEAMKSQPKLPLLDCLLGYYASVTLIAVGILLVTSSFLALGFIGTFLGDYFGILMETKVTSFPFNVTENPMYWGSTSIYFGWSLMNASPVGLVLTVVVTLCYAVALLYEGPFTEEIYRNKAPKSK",
"proteome": "UP001652622",
"gene": "PEMT",
"go_terms": [
{
"identifier": "GO:0008757",
"name": "S-adenosylmethionine-dependent methyltransferase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006656",
"name": "phosphatidylcholine biosynthetic process",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "1d9a6873267fbe30f852dd2ebe128eea30ccf9df",
"counters": {
"domain_architectures": 18289,
"entries": 8,
"isoforms": 0,
"proteomes": 1,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"profile": 1,
"cathgene3d": 1,
"panther": 1,
"pirsf": 1,
"hamap": 1,
"pfam": 1,
"interpro": 2
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 18289
}
}
}