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{
    "metadata": {
        "accession": "A0A6P6IN67",
        "id": "A0A6P6IN67_PUMCO",
        "source_organism": {
            "taxId": "9696",
            "scientificName": "Puma concolor",
            "fullName": "Puma concolor (Mountain lion)"
        },
        "name": "C-X-C chemokine receptor type 3",
        "description": [
            "Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response. Binds to CCL21. Upon activation by PF4, induces activated T-lymphocytes migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling"
        ],
        "length": 593,
        "sequence": "MGPAVALGQPGANCLPAPGNVRHSRGSSRVLHVQASSLPLLQPGGRTALGWNVASFHASSPAREAVVVGLESLGPHAASSCYLPNTWADASLSTSSSTSTSATTTSRQPFSEQWAGAFGTGTPGDILRIYERGCEAADAERKGEEMAPFPVCGWVPPQQRSQGNGPGVPVASVLGRSGIDKPMEEAAANNHVKPSLPPCSADRNWGLPDRGATPGNAQRSPLPPSLPLQMSEHQVFDASELAFLLENCSSSYDYAENESDSCCASPPCPQDFSLNFDRAFLPALYSLLFVLGLLGNGAVAAVLLSQRAALSSTDTFLLHLAVADALLVLTLPLWAVDAAVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLSIVHATQLYRRGPTARVALTCVVVWGLCLFFAIPDFVFLSARRDERLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYARILAVLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVMVDTLMDLEALSRNCGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLTRLGRPDLRGHQRQPASFRRDSSWSETTEASYSGL",
        "proteome": "UP000515131",
        "gene": "CXCR3",
        "go_terms": [
            {
                "identifier": "GO:0016020",
                "name": "membrane",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0004930",
                "name": "G protein-coupled receptor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0007186",
                "name": "G protein-coupled receptor signaling pathway",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0016494",
                "name": "C-X-C chemokine receptor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0002685",
                "name": "regulation of leukocyte migration",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0006935",
                "name": "chemotaxis",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0006954",
                "name": "inflammatory response",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0004950",
                "name": "chemokine receptor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "587fa3dbe4504dc051049f3cca904dd9ab631b87",
        "counters": {
            "domain_architectures": 394800,
            "entries": 15,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 1,
                "cathgene3d": 1,
                "cdd": 1,
                "profile": 1,
                "pfam": 1,
                "panther": 1,
                "prosite": 1,
                "prints": 3,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 394800
        }
    }
}