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{
    "metadata": {
        "accession": "A0A6P6ERS5",
        "id": "A0A6P6ERS5_OCTDE",
        "source_organism": {
            "taxId": "10160",
            "scientificName": "Octodon degus",
            "fullName": "Octodon degus (Degu)"
        },
        "name": "24-hydroxycholesterol 7-alpha-hydroxylase",
        "description": [
            "A cytochrome P450 monooxygenase involved in neural cholesterol clearance through bile acid synthesis. Catalyzes 7-alpha hydroxylation of (24S)-hydroxycholesterol, a neural oxysterol that is metabolized to bile acids in the liver. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase)"
        ],
        "length": 476,
        "sequence": "MSEDLHPGVAALAALLAGVALLLVLRRRGSRRPPCTAGWIPWVGAGLRFGKAPLEFIEQARAQYGPVFTIFAMGKRMTFVTEEEGINVFLKSKEVNFELAVQNPVYHTASIPKNVFLTLHEKLYITMKGKMGAFNVYRFAEQLNEEFHERLEDLGPHGTMDLISLVRHLLYPVTVNVLFKKALFLSYKKKTEDFCQHFQIYDEGFECGSQMPEWLLRNWSKSKRWLLALFEESIPDIKAYKPERADSMTLMQAVLDVVEGVAAGHSASCALLMLWASLSNAVPVTFWTLAFILSHADIHKTIVEGISSVLGGAGKEKIRVTQDTLKKLSLIKWCILEAIRLRAPGVITRKVVKPVKILNYTVPSGDLLMLSPFWLHRNPQYFPDPESFKPERWKEADLEKHAFLEHYMAFGGGKFQCPGRWFALLEIQICIILILYKYDCSLLDPFPMQRFYWEQKIETCAHPYLEAHPGRGERSR",
        "proteome": "UP000515203",
        "gene": "LOC101592465",
        "go_terms": [
            {
                "identifier": "GO:0004497",
                "name": "monooxygenase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005506",
                "name": "iron ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016705",
                "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0020037",
                "name": "heme binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "a02e61ba6c64bb9a9c779746e03a6c43264a16fb",
        "counters": {
            "domain_architectures": 520850,
            "entries": 11,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 0,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "pfam": 1,
                "panther": 1,
                "pirsf": 1,
                "prints": 1,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 520850
        }
    }
}