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{
    "metadata": {
        "accession": "A0A6P6EJN7",
        "id": "A0A6P6EJN7_OCTDE",
        "source_organism": {
            "taxId": "10160",
            "scientificName": "Octodon degus",
            "fullName": "Octodon degus (Degu)"
        },
        "name": "3'-5' RNA helicase YTHDC2",
        "description": [
            "3'-5' RNA helicase that plays a key role in the male and female germline by promoting transition from mitotic to meiotic divisions in stem cells. Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs that plays a role in the efficiency of RNA processing and stability. Essential for ensuring a successful progression of the meiotic program in the germline by regulating the level of m6A-containing RNAs. Acts by binding and promoting degradation of m6A-containing mRNAs: the 3'-5' RNA helicase activity is required for this process and RNA degradation may be mediated by XRN1 exoribonuclease. Required for both spermatogenesis and oogenesis"
        ],
        "length": 1434,
        "sequence": "MSRPSSVSPRPPAAGGGVGGGGGGSVACGSGGGRRAKGLKDIRIDEEVKIAVNIALERFRYGDQREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQIPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIHIQGRPFEVKEMFLEDILRSTGYTNKEMLKYKKEKQREEKQQTTLTEWYSAQDNTFKPESQRQRTVPNVTEEYDLLDDGGDAVFSQLSEKDVNCLEPWLIKEMDTCLSDIWLHKDVDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSASLEFGNLDESSLVQTDGNDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDTGAVLIFLPGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQKKVLKTPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAVQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPINCTIADFLMKAPEPPPTLIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLSAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGTFSDHMALLRAFQAWQKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENVVLTGPKEKKVRFHPTSVLSQPQYKKIPPANGQVAAIQALPTDWLIYDEMTRAYRIANIRCCSAVTPVTVVVFCGPSRLASNALQEPSSFRADGIPNDSSDSEMEDRTTANLAALKLDEWLNFKLEPEAANLLLQLRQKWHSLFLRRMRAPSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWKANNSRKSAADCEFSDESTTAERVLMKSPSAALHPPQKYKDRGILHPKRSTDDRSDQSSVKSTDSSSYPSPCASPSPPSSGKGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSMVYLVFSVQGSGHFQGFSRMSSEIGREKSQEWGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQELEPQNSPVEDIMPITTIECTDFKKLI",
        "proteome": "UP000515203",
        "gene": "Ythdc2",
        "go_terms": [
            {
                "identifier": "GO:0003676",
                "name": "nucleic acid binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003723",
                "name": "RNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "972484cd8d8f5dd28519713c3977f75af841ea07",
        "counters": {
            "domain_architectures": 472,
            "entries": 45,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 9,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 6,
                "smart": 4,
                "cathgene3d": 5,
                "cdd": 4,
                "ssf": 3,
                "pfam": 8,
                "panther": 1,
                "interpro": 14
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 472
        }
    }
}