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{
    "metadata": {
        "accession": "A0A6P5LRV8",
        "id": "A0A6P5LRV8_PHACI",
        "source_organism": {
            "taxId": "38626",
            "scientificName": "Phascolarctos cinereus",
            "fullName": "Phascolarctos cinereus (Koala)"
        },
        "name": "Translation initiation factor eIF2B subunit epsilon",
        "description": [
            "Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on eukaryotic initiation factor 2 (eIF2) gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed"
        ],
        "length": 718,
        "sequence": "MAATAAASRGGKRAGGTGGQGGGAAGRGAEEEAPPPLQAVLVADSFNRRFFPISKDRPRALLPLANVALIDYTLEFLTATGVQETFVFCCWKAPEIKEHIHKSKWCLPTSPNVVRIVTSETYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINISHALEEHRSRRKREKNVSVMTMIFKESSPSHPTRCPEDNVVVAVDSTTHRVLHYQKTHGLRRFSFPLSLFRGSGEGVDIRYDLLDCHISICSPQVAELFTDNFDYQTRDDFVRGLLVNEEVLGNHIHMHVTTREYGARVSNLRMYEAVCADVVRRWVYPLTPEMNFTDSPAQSCTHSRHNIYRGLEVSLGHGSVLEENVLLGAGTVIGSNCTIKNSVIGPDCHIGDNVLLDQAYLWQGVRVASGAQIRQSLLCDHSEVKERVILKPRCVLTSQVVVGPDLELPEGSVISLHPPDEEEEDDDSQFSDDSGADRTERVKSTGYSPSDVGAAGQGYLWRAQGANPGEEEDEEELRQSLWGLTINMDEESESDSEQSLGSQELDSRAGSPQLDDIRVFQNEVAGTLQRGQEENISCDNLVLEINSLKYAYNISLKEVMQVLSQVVLEFPLEQLNSQLDPNCYCGLLLPLLRAWSPVFKNYIKRTGDHLQALTAIEEFFLEHDSLVTSLAKVLMTFYELDILAEETILQWFHQKDVPDKGKQLRKNQRLQNFIQWLKEAEEESSDEQD",
        "proteome": "UP000515140",
        "gene": "EIF2B5",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005085",
                "name": "guanyl-nucleotide exchange factor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0031369",
                "name": "translation initiation factor binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0009058",
                "name": "biosynthetic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "07bf0236dc6e7930a4a95a7ed51d9e566657e9b4",
        "counters": {
            "domain_architectures": 2427,
            "entries": 24,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 6,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 3,
                "ssf": 3,
                "cdd": 3,
                "pfam": 3,
                "profile": 1,
                "smart": 1,
                "panther": 1,
                "interpro": 9
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 2427
        }
    }
}