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{
    "metadata": {
        "accession": "A0A6P5IR86",
        "id": "A0A6P5IR86_PHACI",
        "source_organism": {
            "taxId": "38626",
            "scientificName": "Phascolarctos cinereus",
            "fullName": "Phascolarctos cinereus (Koala)"
        },
        "name": "Dynein axonemal heavy chain 12",
        "description": [
            "Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly"
        ],
        "length": 3728,
        "sequence": "MSDDEDKEDKDVIAAEKEALNLKLPPIMYPPEEIGADTPLQSKLLKFRRVKEQGKRLNQIITVGAIKKHMRISEEKKKRSPIAPEPEYPSTMYSDLRRRGENYIFMKKRVESHPIVPIQREWLDNMLKLVPQSLKNGREREQLVENLLNEVTTEFERSMKRYLVRTVLVRPPVSWLEDEGGPLPESPLGLDYSKPWHSNYVQARSQVSENLHVLHPTLRTLLDLGYTTFANRLLLDLTGFRAKGPMDCESLRNDVSINARKTEEKLMNTWYPKVINIFTKKEAHDDIKAEKLDSFYNCVSTLMSNQLRDLLKRTVEGFVNLFDPNDNKWLPIFKMELTFDDEKMDFYPTFQDLQEVVGGVVDWIGETLKNVQTVQSWLAGGPTTVKLNTDLPDHMLDQAFRTLREAVNLNLQGPKEHFNEYVEKYSWLINGTAVDQIQTFQAEDHTFDEYTERIEYFLNLAKEIMMLPNLAHFPMILLDCDDLKEGLVNKVKGYANLLLNDIATKHRNENESICIEFENIKEHALKVPETTEEMMELISYVENARTKGVQELALRIQECQRRTNYLLDVFMFPPEDLDLNASVLLWPRNMNPIFNENDELIENAKRKGETDLVTKREKLILEIEKETRRMGEFTEYAELEWMQQYVMDVRLLQKRIQEAEDMVAFINKEEGLFKWELTKYPELDKLKVSVEPYQKFFSFILKWQRTEKRWMDGGFLDLNGESMETDVDEFFREIYKSLRFFQLKQKKEAQEKRKAAGKRSIIDEKIEEDIQDNPTVVMCSAVMEQIKAFKEYIPTVTILCNPGLRARHWKEMSEIVGYDLTPDSGTTLRKVLKLNLDPYLEKFEVISAGASKEFSLEKAMHTMINTWDDIAFHISPYRDTGVSILSAVDEIQTILDDQIVKTQTMRGSPFIKPFEEEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQMVDRHWRDVMKYCAKDPKVLAATSLTGLLDKLQNCNDLLDKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFLPNLDIRAMYSTEGERVELISLISTAEARGAVEKWLIQVEDLMLKSIHQVIALSRMAYPQSERKDWVQEWPGQVVLCVSQMYWTIQTQESISSEPEGLKSYYNHLQLQLNDIVGLVRGKLSKQTRITLGALVTIDVHARDVVMDMIEMGVSTNTDFQWLAQLRYYWEWENVRVRIINCNVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQLKLEVFNFEGTELKLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNAKLLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKFPNENEDILLLRSIRDVNEPKFLSHDIPLFNGITSDLFPSVKLPEADYNDFLECAHECCKAHNLQPVKVFLDKMIQTYEMMIVRHGFMLVGEPYAGKTKVLHVLADTLTLMNERSYGEEEKVIHRTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSAQMSLIFEAMDLSQASPATVSRCGMIYMEPLQLGWEPLVTSWLHTLKEPLDRKEYQELLQELFDWLIPSALRVRQKKCKELIPTSNSNVVISLTRLFEVLLCKVAAEDPNGKHIRVWIMACFIFSLIWSIGGTCDTDGRLVFDSFIREIITGKNEEHPIPPGVGKWECNFDERGLVYDYTYEMKNRGRWIHWNELIRTTSLGEKKAKIQEIIVPTMDTIRYTFLMDLCLTYEKPLLFVGPTGTGKSVYVKNKLMHHLNRDQYFPFFVNFSARTSANQVQNIIMARLDKRRKGVFGPPMGKKCVIFIDDMNMPALEKYGAQPPIELLRQFFDYGNWYDLKDTTKILLVDTQLIAAMGPPGGGRNPVTPRFIRHFNICSINTFSDETMVRIFSAIVAFYLRTREFLPEYFAVGNQIVSGTMEIYKRSMENLLPTPAKSHYTFNLRDFSRVILGCLLINKEVVESKHTMVRLFVHEVLRVFYDRLVDDYDRAWLFQLIKVVIKDHFKENFDTVFSHLRKGNAPVKEEDLRSLLFGDYMNPDLEGDERIYTEIPNVKHFSDVVEQCLEEYNQTHKTRMHLVIFRYVLEHLSRICRILKQSGGNALLVGLGGSGRQSMTRLATSMAKMHLFQPEISKSYGMNEWRDDLKNLLRSAGMKGLKTVFLITDTQIKEEAFLEDVDSVLNTGEVPNIFAADEKQEVMEGVRPAAQAGIKHGELSPLALFAFFVNQCRDNLHVVVAFSPIGDAFRNRLRQFPSLINCCTIDWFQPWPDDALERVAVKFLETLELTKNERLEVVPICKHFHTSIMDLSARFLQDLGRHNYVTPTSYLELIAAFRQLLTQKRQAVMKSKFRYTNGLDKLDFAESQVGEMKLELVQLQPRLEEAKVENANMMKVIEAESAQVEAKSRFVKIDEELATGKAEEAQALKNECESDLAEAIPALEAALSALDTLKPADITIVKSMKNPPSGVKLVMAAICVMKDIKPEKITDPAGTGGKILDYWGPSKKVLGDMNFLRDLKEYDKDNIPVSVMQKIRGEYLTNPEFDPPKVAKASSAAEGLCKWIMAMEVYDRVAKVVAPKKARLAEAQKSLGETMNLLNQKRAELKAVEDRLANLQQTFLEKTEEKVRLEDQVELCAKKLERASKLIGGLGGEKTRWSKAADDLQNTYDNLTGDVLISAGVIAYLGAFTAGFRHECTKDWSRLCKEKEIPCSDDFSLSKILGDPVKIRAWNIAGLPTDAFSIDNGVIVSNSRRWPLMIDPQGQANKWIKNSERENQLSVIKLSDSDYMRTLENCIQFGAPLLLENVGEELDPSLEPLLLRQTFKQGGIDCIRLGEVTIEYSFDFKFYITTKLRNPHYMPELATKVSLLNFMITPEGLEDQLLGIVVAKERPELEEERNALILQSAANKKQLRDIESKILETLSSSEGNILEDESAIKVLDSAKLMSNEILKKQQIAEKTEIKIAESREGYRPIAKHSSVLFFSIADLANIDPMYQYSLSWFVNLYINSIHDSNRSKILEKRLRYLNDHFTYNLYCNVCRSLFEKDKLLFSFLLCANLLLAKKEIEYSEFMFLLTGGIGLKSPEGNPDPTWLPEKSWEELCRASELPAFKDLREHFQKNIGDWHEIYDSKEPHMVPFPKPLDTNLNELQKIIVLRCLRPDKISPAITNYVTDKLGKKFVEPPPFDLAKSYLDSNCTIPLIFVLSPGADPMASLLKFANDKNMSANKFQAISLGQGQGPIAARMIRESIEEGTWVCLQNCHLAVSWMPMLEKICEDFSAETCQPAFRLWLTSYPSEKFPVTILQNGVKMTNEPPTGLRLNLLQSYLTDPISDLQFFKGCPGKEQVWEKLLFGVCFFHALVQERKKFGPLGWNIPYGFNESDLRISVRQLQLFINEYEDVPFEAISYLTGECNYGGRVTDDWDRRLLLTILADFYNPEIIKNPHYMFSPSGNYYAPPRGTYDDYIEFIKKLPFTQQPEIFGLHENVDISKDLHQTKTLFESLLLTQGGTTQSGSSASADATLLEITHDILGKPEQNDPPHFAQPGESDQGAGGYGFGA",
        "proteome": "UP000515140",
        "gene": "DNAH12",
        "go_terms": [
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0008569",
                "name": "minus-end-directed microtubule motor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0007018",
                "name": "microtubule-based movement",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0030286",
                "name": "dynein complex",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0045505",
                "name": "dynein intermediate chain binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0051959",
                "name": "dynein light intermediate chain binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "3c08b58af4e7a833f0a00e3390cb0cb7c8f247cb",
        "counters": {
            "domain_architectures": 123,
            "entries": 42,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 12,
                "pfam": 10,
                "ssf": 1,
                "smart": 1,
                "cdd": 1,
                "panther": 1,
                "interpro": 16
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 123
        }
    }
}