General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "A0A6J3S3C9",
        "id": "A0A6J3S3C9_TURTR",
        "source_organism": {
            "taxId": "9739",
            "scientificName": "Tursiops truncatus",
            "fullName": "Tursiops truncatus (Atlantic bottle-nosed dolphin)"
        },
        "name": "Selenocysteine-specific elongation factor",
        "description": [
            "Translation factor required for the incorporation of the rare amino acid selenocysteine encoded by UGA codons. Replaces the eRF1-eRF3-GTP ternary complex for the insertion of selenocysteine directed by the UGA codon. Insertion of selenocysteine at UGA codons is mediated by SECISBP2 and EEFSEC: SECISBP2 (1) specifically binds the SECIS sequence once the 80S ribosome encounters an in-frame UGA codon and (2) contacts the RPS27A/eS31 of the 40S ribosome before ribosome stalling. (3) GTP-bound EEFSEC then delivers selenocysteinyl-tRNA(Sec) to the 80S ribosome and adopts a preaccommodated state conformation. (4) After GTP hydrolysis, EEFSEC dissociates from the assembly, selenocysteinyl-tRNA(Sec) accommodates, and peptide bond synthesis and selenoprotein elongation occur"
        ],
        "length": 585,
        "sequence": "MAGRRVNVNVGVLGHIDSGKTALARALSTTASTAAFDKQPQSRERGITLDLGFSCFSVPLPARLRPAPLGAEPEPGAEPRLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKTDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAPIIPVAARPGGPDAPETEAPQGIPELIELLTSQISIPRRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSVSLGDSVEIPTLKVVRKVKSMQMFHTPVTSAVQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALVSVEKIPYFRGSLQTKAKFHITVGHETVMGRVMFFSPAPDGFDHEPVLDSFDFSQEYLFQEQYLCPGSVPAETDGGEADRRVGQASEGRCPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHANTCRLAFHGVLLHGLEDKNYAESALPRLRVYKLKHKHGIVERVMDDYSVIGRSLFKKETNIQLFVGLKVQLSTGELGVIASAFGQSGKFKVHIPGGLSPESKKILTPTLKKRGRAGRGEEAGQPEPVQHVALSLSFKRYVFDTHKRMVQSP",
        "proteome": "UP000245320",
        "gene": "EEFSEC",
        "go_terms": [
            {
                "identifier": "GO:0003924",
                "name": "GTPase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005525",
                "name": "GTP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "19254744b5c31bee03c0fad44548a0c3f9abc80b",
        "counters": {
            "domain_architectures": 1142,
            "entries": 21,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 6,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 1,
                "cathgene3d": 2,
                "ssf": 2,
                "cdd": 3,
                "pfam": 4,
                "panther": 1,
                "prints": 1,
                "interpro": 7
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1142
        }
    }
}