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{
    "metadata": {
        "accession": "A0A6J3R7M3",
        "id": "A0A6J3R7M3_TURTR",
        "source_organism": {
            "taxId": "9739",
            "scientificName": "Tursiops truncatus",
            "fullName": "Tursiops truncatus (Atlantic bottle-nosed dolphin)"
        },
        "name": "DNA-binding protein RFX2",
        "description": [
            "Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export",
            "Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Probably activates transcription of the testis-specific histone gene H1-6"
        ],
        "length": 1242,
        "sequence": "MQNSEGGSDSPASVALCPSSAAQAPVAQPVPASPQRVLVQAAGSAPKGAQMQPISLPRVQQVPQQVQPVQHVYPPQVQYVEGGEAVYTNGALRTAYAYNPEPQMYAPSSSASYFEAPGGAQVTVAGSSPTAVPAHSMVGITMDVGGSPIVSGTGAYLIHGGMDGTRHALAHTSRSSPATLEMAIENLQKSEGITSHKSGLLNSHLQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPVHQKPRYRPAQKTDSLGESGSHGSLHSTPEQAMAAQSQHHQQYIDVSHVFPEFPAPDLGSVLLQENITLHDIKALQLAYRRHCEATLDVVMNLQFHYVEKLWLSFWNSKASSGDGPASLPTSDEEPEGAVLPKDKLVSLCKCDPVLRWMRTCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKSLEGWLTNAMSDFPQQVIQTKVGVVGAFAQTLRRYTSLNHLAQAARAVLQNTAQISQMLSDLNRVDFANVQEQASWVCQCEEGVVQRLEQDFKLTLQQQSSLDQWASWLDNVVTQVLKQHAGSPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAEATGETPIAVMGEFNDLASLSLTLLDKVFQEKPAIAPPVFVFQKDKGQKSSAEQKDLSDSGEESRGEAEAPHHGTGHPESAGEHALELPAPASASASAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEEKSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKVLSQTVPSSGTNGVSVPADCPGAATSASPDNPARRSPSDEAPALEEKDLQKNESSSASEESCEKKELAQQAFVFGQNLRDRVKLINENAEVVDMENAGHPSSEAPAATNYFLQYISSSLESSANSADAASSKFIFGQNMSERVLSPPKLNEVSPDANRENTVAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQIQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQMDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSHVEQEQEARTPAPEPGAAPSNEDDSDDDDVLAPSGATGGGAGDEGDGQTAGST",
        "proteome": "UP000245320",
        "gene": "LOC101333468",
        "go_terms": [
            {
                "identifier": "GO:0003677",
                "name": "DNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006355",
                "name": "regulation of DNA-templated transcription",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0046907",
                "name": "intracellular transport",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005634",
                "name": "nucleus",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0003700",
                "name": "DNA-binding transcription factor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "b9e32f2bcf3fb7d3636d112ec34e534bad542af9",
        "counters": {
            "domain_architectures": 6,
            "entries": 21,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "pfam": 4,
                "cathgene3d": 2,
                "profile": 2,
                "ssf": 2,
                "smart": 1,
                "cdd": 1,
                "panther": 1,
                "interpro": 8
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 6
        }
    }
}