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{
    "metadata": {
        "accession": "A0A6J2VF67",
        "id": "A0A6J2VF67_CHACN",
        "source_organism": {
            "taxId": "29144",
            "scientificName": "Chanos chanos",
            "fullName": "Chanos chanos (Milkfish)"
        },
        "name": "Proteasome activator complex subunit 4B isoform X2",
        "description": [
            "Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. involved in DNA damage response in somatic cells: binds to acetylated histones and promotes degradation of histones"
        ],
        "length": 1827,
        "sequence": "MKKDPVETIGFIPQKDIIYNKLLPYADRLDNESNELLAKIKGNLGRAVQLRELWPGVLFWTRKLSTYLRLYGRKFSKEDHVLFIKLLYELVTIPKLEISMMQGFARLLINLLKKKELLSRDDLELPWRPLYELYERILYSKTEHLGLNWFPNSVENVLKTLVKSCRPYFSESATQEMLDEWRPLLCPFDVTMQKAVGYFELFLPTIMPPEQHDKGFKLWFDELMDLWVSVQNLPSWEGNLVNLFARLANDNIGYVNWDPYIPKIFTRILRSFNLPVGSSQMIVPRYLTNSYDIGHVVLWISSMLGGPGNQAQKQLNGLFSSIASFYHPSNNGRWLMKLMKLLQRLPASVVRRLHRERYKKPCWITPVPASHRLTDQDVTDFVESMKQPVLMAMFSKTGSMDAAQALQNLALMRPELVIPPVLEKTYPAMETLTEPHQLTATLSCMIGMARSLLSGGRHYPEGPAHVLPLLMRALPGVDPNDFSKCMITFQFIATFTTLVPLVDCSSALHEKNDLTEMERELCSASAEFEDFVLQFMDRCFALIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSMEIFKVALEKVFNFATTNIFETRVAGRMVADMCRAASKCHPAESLRLFVPHCCSAITHITANEDVLNEEELDKELLWNLQLLSEVTRVDGEKLLPYRAQLVQILQLTLRLRCKQGYSLACNLLHHILRSTALIYPTDYCSVPGGFSRPLSEYLPIKDWGRPGDLWDLQIRWHVPSAEETEFVFYVLDLLLQPELQRLQRYAQGEQDMSRDDVLQSLSIVQHCLLGAGSMLPPLDGPPVTGLVPSLVSLEETKLFIGVNYDESRENYREAICKVMRQLLHHILEHSEDDTKSLFAIIKIISDLMHFKGSHKHEFDSRWKSFTLVKKSMENRLHGKKQHIRALLIDRVLLQHEMRKLLVEGCEYKTIHQDLLKDLLRLSTSTYSQVRSKAQSVFFTALGAYNFCCRDITPQVLQLLDPNRTDVTQQQFKGALYCLLGNHSGVCLGNLHDWDCIALTWPAMVRSGLSVAMSLEKPSIVRLFDDLADKVHRQYETIGIDFAVPDSTVLLAGRITESKAPVPNPGTPTDQEIEQGIALQQAKNLDSVQKYERLVSDLLECLDDRDLPWKFEHMAIGFLSLLLRDDHPLPAPAVLFFVQSLNHDALIVRKMAISSVGGILKQLKRPRKKVAVCPSEISGVTEPEGLIAGDRPGNEWLQYDTNKLPRSQQDWENFHFVEKTHWGYYTWPKKLMLYAPTAEQPNDLTPEDMNERERIIYDHFSDPGFIAQLIEFLALEDRKGKDKFNPRRFCLFKGLFRNYTDAFLPVLRPHMERLANDSHESTQRCVAEIIAGLVRGSKHWGYSKVEALWDFLIPLMRTALSKITVETYTDWGTCVATACESRDPRKLHRLLEMLMECPLSGEGGSFVDACHLYVLQGGLAQQEWRVPELLHRLLCYLEPKLTQVYKNVRERIGSVLTYIFMIDVMLPHTLPTKSPHISEFTQRVMCRLKPLLEGEEEIQNHVVEENGVGEQDERTQAIKLLKTVLKWLMASAGRSFSTPVSQQLQLLPLLFKIAPVENDDSYDELKRDAKTCLSLMSQGLLYPEQIPLVLQVLKEIAGSSSWHARFSVLTYLQIMVFYNLFTMLSSEQAVRDVRALVIRLLEDEQLEVREMAATTLSGFLQCNFLAMDASMQTHFEALCKTRLPKKRKRDRGSIVDTIPSVDLVRRHAGVLGLSACILSSPYDVPTWMPQLLMDLSAHLNDTQPIEMTVKKTLSNFRRTHHDNWLEHKQQFTDDQLLVLTDLLVSPCYYA",
        "proteome": "UP000504632",
        "gene": "psme4b",
        "go_terms": [
            {
                "identifier": "GO:0016504",
                "name": "peptidase activator activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0070628",
                "name": "proteasome binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "7dfbb416ec31b39ccd5b9431745d09aa6d981790",
        "counters": {
            "domain_architectures": 2499,
            "entries": 12,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 1,
                "pfam": 3,
                "cathgene3d": 1,
                "panther": 1,
                "interpro": 6
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 2499
        }
    }
}