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InterPro-Version: 108.0
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{
    "metadata": {
        "accession": "A0A6J2LHX2",
        "id": "A0A6J2LHX2_9CHIR",
        "source_organism": {
            "taxId": "89673",
            "scientificName": "Phyllostomus discolor",
            "fullName": "Phyllostomus discolor (pale spear-nosed bat)"
        },
        "name": "Integral membrane protein 2",
        "description": [
            "Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation"
        ],
        "length": 271,
        "sequence": "MVKISFQPAVAGVKGDKADKASASASAAAPATGPAAEILLTPAREERPPYHRHKKGGSVGSVCYLSMGMVVLLMGLVFASVYIYRYFFLAQLARDNFFHCGVFYEDSLSSQAHTRMELEEDVKIYLEDNYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIELNTTIVLPPRNFWELLMNVKRGTYLPQTYIIQEEMVVTEHVSDKEALGSFIHHLCNGKDTYRLRRRATRRRISKRGAKRCNAIRHFENTFVVETLICGAA",
        "proteome": "UP000504628",
        "gene": "ITM2C",
        "go_terms": null,
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "883524b6fbdaf50d6c9f78577c11053e90ab5e79",
        "counters": {
            "domain_architectures": 7990,
            "entries": 7,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "smart": 1,
                "profile": 1,
                "pfam": 1,
                "panther": 1,
                "interpro": 2
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 7990
        }
    }
}