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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A6J0I6L1",
"id": "A0A6J0I6L1_9PASS",
"source_organism": {
"taxId": "321398",
"scientificName": "Lepidothrix coronata",
"fullName": "Lepidothrix coronata (blue-crowned manakin)"
},
"name": "Prosaposin",
"description": [
"Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate",
"Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases",
"Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12)"
],
"length": 522,
"sequence": "MARLLLLNLLGLLAAAVASPVLWQKECVKGPEVWCQSIRKASQCGAVKHCQQNVWNKPAVSSIPCDLCKELVTVAGKVLKDNGTEEEIRSYLEKTCEFLPDQGLVSECKEIVDSYLPVIMDMIKEELDKPEVVCSALALCQSLQKHLATMKLQKQLQTNKIPELDFSELASPFMANVPLLLYPQDKPKQKPKASGDVCQDCIQLVTDVQEAVKTNSSFVKSLVAHAKEECDRLGPGMSDMCKTYISEYSDLAIQMMMHMQPKDICAMVGFCASVKSVPLQPLVPAQVVHEVKMETVEKASVQEKASVQEKTFSLCEICETMVKEVTGLLESNKTEEEIVHEMEVVCRLFPGSVKDQCKDFIEVYGQAVIDMLLEATNPEAVCVMLKCCAANKLPQQPVVVKPAGGFCDICKMVVAYADKELEKNATTAEIEALLEKVCHFLPESVSDQCVQFVEQYEPVVVQLLAEVMDPTFVCTKLGVCESAKQPLLGDNACVWGPGYWCKNMDTAAQCNAVDHCKRHVWN",
"proteome": "UP000504624",
"gene": "LOC108502762",
"go_terms": [
{
"identifier": "GO:0006629",
"name": "lipid metabolic process",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0006665",
"name": "sphingolipid metabolic process",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0005764",
"name": "lysosome",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 4,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "5284db2b0b891bdcd45b15502e475cfcf2808b7e",
"counters": {
"domain_architectures": 793,
"entries": 20,
"isoforms": 0,
"proteomes": 1,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"profile": 2,
"smart": 2,
"cathgene3d": 1,
"ssf": 1,
"pfam": 3,
"pirsf": 1,
"panther": 1,
"prints": 1,
"interpro": 8
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 793
}
}
}