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{
    "metadata": {
        "accession": "A0A6I9PJX5",
        "id": "A0A6I9PJX5_9TELE",
        "source_organism": {
            "taxId": "8208",
            "scientificName": "Notothenia coriiceps",
            "fullName": "Notothenia coriiceps (black rockcod)"
        },
        "name": "18S rRNA (guanine-N(7))-methyltransferase",
        "description": [
            "S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA. Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity. Locus-specific steroid receptor coactivator. Potentiates transactivation by glucocorticoid (NR3C1), mineralocorticoid (NR3C2), androgen (AR) and progesterone (PGR) receptors. Required for the maintenance of open chromatin at the TSC22D3/GILZ locus to facilitate NR3C1 loading on the response elements. Required for maintenance of dimethylation on histone H3 'Lys-79' (H3K79me2), although direct histone methyltransferase activity is not observed in vitro"
        ],
        "length": 282,
        "sequence": "MTSNCRRPEHTAPPDLFYNEVEAKKYSQNSRMIEIQTQMSERAVELLNLPEGQPCFLLDVGCGSGLSGDFLSEEGHYWVGVDISTAMLDVALDREVEGDLLVGDMGHGMPFRPGTFDGCISISALQWLCNADKRSHSPPKRLYTFFSTLYSSLSRGSRAIFQLYPENSEQLELITTQAMRAGFGGGMVVDYPNSSKAKKFFLCLFAGVTGSLPKGLGTETSDRAVSNQVQYSGQRCRFKGMKGKSAKKGRDWILEKKERRRRQGREVRADTKYTARQRKPNF",
        "proteome": "UP000504611",
        "gene": "bud23",
        "go_terms": [
            {
                "identifier": "GO:0008757",
                "name": "S-adenosylmethionine-dependent methyltransferase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016435",
                "name": "rRNA (guanine) methyltransferase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0070476",
                "name": "rRNA (guanine-N7)-methylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "ed1d41360c6cd8cff9c162bf3e76118dd104edb4",
        "counters": {
            "domain_architectures": 3518,
            "entries": 10,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 1,
                "cathgene3d": 1,
                "cdd": 1,
                "pfam": 2,
                "panther": 1,
                "interpro": 4
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 3518
        }
    }
}