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{
"metadata": {
"accession": "A0A671YPY0",
"id": "A0A671YPY0_SPAAU",
"source_organism": {
"taxId": "8175",
"scientificName": "Sparus aurata",
"fullName": "Sparus aurata (Gilthead sea bream)"
},
"name": "Transcription and mRNA export factor ENY2",
"description": [
"Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery",
"Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery"
],
"length": 96,
"sequence": "MSKDSQMRAAINQKLIEMGERERLKELLRAKLVECGWKDQLKAHCKDVIKEKGLEHVTVEDLVTDVTPKGRALVPDSVKKELLQRIRAFLAQHATL",
"proteome": "UP000472265",
"gene": "ENY2",
"go_terms": [
{
"identifier": "GO:0003713",
"name": "transcription coactivator activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006406",
"name": "mRNA export from nucleus",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0045893",
"name": "positive regulation of DNA-templated transcription",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0000124",
"name": "SAGA complex",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "ba9455d725df3ff238858c99315bda05780bc904",
"counters": {
"domain_architectures": 3443,
"entries": 6,
"isoforms": 0,
"proteomes": 1,
"sets": 0,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"panther": 1,
"hamap": 1,
"pfam": 1,
"interpro": 2
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 3443
}
}
}
