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{
    "metadata": {
        "accession": "A0A507ZP21",
        "id": "A0A507ZP21_9GAMM",
        "source_organism": {
            "taxId": "1706195",
            "scientificName": "Marilutibacter aestuarii",
            "fullName": "Marilutibacter aestuarii"
        },
        "name": "Bifunctional ligase/repressor BirA",
        "description": [
            "Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon"
        ],
        "length": 344,
        "sequence": "MRGSLNLGGAVIEERELLERLMAGPVSGDALARASGLSRAAVWKRIQALRDAGVPIQAQAGRGYRLEQPMDLLSPAAILGALDPATAASVHGLEVEWSLDSTNSALLRRAPPVAPGRVEVLMAERQTGGRGRRGRHWASPLAAHLYLSLARGFEGGLARLGGLSLVAGIAVAEALHAFGVDAARLKWPNDIVVEAADGLRKLGGVLVEGGGEHAGPVRAVIGIGLNVRMPPAEAAAIDQPWCDLEALAGPGVDRNRVAATLLSHLLPALDAFDAEGLAPFMARHAALDVLAGRAVRLHGEGVAVRTGTALGLAADGALRVRLDSGECCDVHSGEVSVRRLESPA",
        "proteome": "UP000318212",
        "gene": "birA",
        "go_terms": [
            {
                "identifier": "GO:0036211",
                "name": "protein modification process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0004077",
                "name": "biotin--[biotin carboxyl-carrier protein] ligase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006355",
                "name": "regulation of DNA-templated transcription",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "e323a284b0f9347a27dee67a68aa1033e00ba978",
        "counters": {
            "domain_architectures": 8512,
            "entries": 25,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 4,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 3,
                "pfam": 3,
                "cdd": 1,
                "ssf": 3,
                "profile": 1,
                "hamap": 1,
                "ncbifam": 2,
                "panther": 1,
                "interpro": 10
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 8512
        }
    }
}