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{
    "metadata": {
        "accession": "A0A3P8Z4B5",
        "id": "A0A3P8Z4B5_ESOLU",
        "source_organism": {
            "taxId": "8010",
            "scientificName": "Esox lucius",
            "fullName": "Esox lucius (Northern pike)"
        },
        "name": "Rap guanine nucleotide exchange factor 4",
        "description": [
            "Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2"
        ],
        "length": 978,
        "sequence": "MISPKMVAAHTPGHSSASAEWIICLDKRPAERSGEDVDIILSRLKRVKAFERFHPSLLQQICLCGFYECLEKGITLYRQGDTGTSWYAVLSGSLDVKVSETANHQDAVIICTLGIGTAFGESVLDNTPRHATIVTREFSELLRIDQREFKSLWEKYRRCMAGLLAPPYGVMESGGPSTDRMPDKENISNNSCVSISKHLNKVPSEKILRAGKVLRDAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWQMQHSSCVHSRNQAVGMWQVLLEEGVLNHVDQEPTFQDKYLFYRFLDDEKEDAPLPTEEETRENQEELQDTLLLLSQIGPDAHMRMILRKQPGQRTADDLEIIYEELLHIKALSHLSTSVKRELAGVLIFESHAKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRSASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKSPSSSSRTSTYTVMSGTPEKILEHFLEMMRLDSDLNESPDAVASQGSEQERLDYALNNKRRVIRMVLRWAGVHGDQLQEEDVSLAFLEEFFESVCDDASVIPALKDQLPELENIVKKQKHICLAVLFQHKVLLRQFSMGDEKLQKRVPIKSHDEILFKVHCSDHTYTTIRVPVAASVREVVSAVADKLGSAEDLLLVNLSSAGGEKVVLKPNDISVFSTLSINGRLFVCPRDQLDSLTPLPEQEGPTAGSMASFELMSSKDLAYQMTVYDWELFHCVHEHELIYHTFGRQNFQKTTANMDLFLRRFNEIQLWVITEICLCAQLSKRVQLVKKFIKIAAHCKEYKNLNSFFAIIMGMSNPAVSRLSQTWEKLPSKFRKFYSEFESLMDPSRNHRVYRLTVAKLDPPIIPFMPLLIKDMTFTHDGNKTFTDSLVNFEKMRMIANTVRIVRYCRSLPFKPSQTSKNHPDVRSYVRQLAVIDNQRTLSQLSQRLEPRRT",
        "proteome": "UP000265140",
        "gene": "RAPGEF4",
        "go_terms": [
            {
                "identifier": "GO:0035556",
                "name": "intracellular signal transduction",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005085",
                "name": "guanyl-nucleotide exchange factor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0007264",
                "name": "small GTPase-mediated signal transduction",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "69a338f809e0d08803848d60e48b8cfaaaf60d61",
        "counters": {
            "domain_architectures": 227,
            "entries": 36,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 5,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 5,
                "ssf": 4,
                "profile": 3,
                "cdd": 3,
                "smart": 3,
                "pfam": 3,
                "panther": 1,
                "prints": 1,
                "prosite": 1,
                "interpro": 12
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 227
        }
    }
}