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{
    "metadata": {
        "accession": "A0A315V709",
        "id": "A0A315V709_GAMAF",
        "source_organism": {
            "taxId": "33528",
            "scientificName": "Gambusia affinis",
            "fullName": "Gambusia affinis (Western mosquitofish)"
        },
        "name": "Bifunctional purine biosynthesis protein ATIC",
        "description": [
            "Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis. Acts as a transformylase that incorporates a formyl group to the AMP analog AICAR (5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) to produce the intermediate formyl-AICAR (FAICAR). Can use both 10-formyldihydrofolate and 10-formyltetrahydrofolate as the formyl donor in this reaction. Also catalyzes the cyclization of FAICAR to inosine monophosphate (IMP). Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization"
        ],
        "length": 591,
        "sequence": "MASTELALLSVSDKTGLVDFAKRLVNVGLSLVGSGGTAKALRDAGLAVRDVSELTGHPEMLGGRVKTLHPAVHGGILARKSASDSADMEKLGYSLVRVVVCNLYPFVKTISSPNVTVEDAVEQIDIGGVTLLRAAAKNHARVTIVCDPADYSLVAKEMENSGHKDTTLETRRTLALKAFTHTAQYDEAISDYFRGQYSRGVSQLPLRYGMNPHQAPAQIFTLRSELPLKVANGSPGFINLCDALNAWQLVRELKAALGVAAATSFKHVSPAGAAVGVPLSEEEAKVCMVHDMLKDLTPLATAYARARGSDRMSSFGDFIALSDVCDVPTAKIISREVSDGIIAPGYEEEALKILSKKKNGNYCVLQMDPDYEPDSTEVRVLFGLYLKQKRNGALINKEFFRNVVSEGSLSEDALRDLTVATIAVKYTQSNSVCYAKAGQVIGIGAGQQSRIHCMRLAGEKADNWWLRHHPRVLSMKFRGGVKRAEMANAIDQFVSDTVGEGPDLDVWKSMYDEVPEFLSATEKKNWISSLQGVAVSSDAFFPFRDNIDRAKRSGVEYIAAPAGSAADEVVINACNELGITLVHTSLRLFHH",
        "proteome": "UP000250572",
        "gene": "CCH79_00004961",
        "go_terms": [
            {
                "identifier": "GO:0003937",
                "name": "IMP cyclohydrolase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0004643",
                "name": "phosphoribosylaminoimidazolecarboxamide formyltransferase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006164",
                "name": "purine nucleotide biosynthetic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "4c4a53bb5204d60810708c65aa3b11581b73dfb8",
        "counters": {
            "domain_architectures": 28631,
            "entries": 22,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 1,
                "cathgene3d": 3,
                "cdd": 1,
                "ssf": 2,
                "pfam": 2,
                "smart": 2,
                "pirsf": 1,
                "hamap": 1,
                "panther": 1,
                "ncbifam": 2,
                "interpro": 6
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 28631
        }
    }
}