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{
    "metadata": {
        "accession": "A0A2U9C7U1",
        "id": "A0A2U9C7U1_SCOMX",
        "source_organism": {
            "taxId": "52904",
            "scientificName": "Scophthalmus maximus",
            "fullName": "Scophthalmus maximus (Turbot)"
        },
        "name": "Phosphodiesterase",
        "description": [
            "Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart. Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein. In brain, involved in cognitive function, such as learning and long-term memory"
        ],
        "length": 509,
        "sequence": "MGSASSSYRVIYLDVEGRTQKVVFSRFCSPCDIKDLFCTALGVPRNTNLSLLDSSGAMVSIDPTMPHNTERSPYRVLPMTGGQLADKEELFQNVLTQVAEQFSRAFKINELKSEVTNRLAMLEKRVELEGMKVVEIEKCRTDIKKLRVEMASRNNSNFLEDTKKLTPRRDVPSYPKYMLSEQTIEALKKPAFDVWLWEANEMLSCLEHMYHDLGLVTDFNINPITLKRWLLSIHDNYKNNPFHNFRHCFCVTQMMYSMICLCSLQEKFTQVDILILMTAAVCHDLDHPGFNNTYQINARTELAVRYNDISPLENHHCAVAFQIFSQPDCNIFSSFDPEAFKQLRQGTITLILATDMARHGEILDSFKQKVDSFDFTDEEHATCLKMVLIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKTEGLPVAPFMDRERVTKPTAQIGFIKFVLIPMFESVMKLFPQIEEAMVQPLRESRDRYEELKQIDDAMNEVQKKKSESLTMGGKKK",
        "proteome": "UP000246464",
        "gene": "PDE9A",
        "go_terms": [
            {
                "identifier": "GO:0004114",
                "name": "3',5'-cyclic-nucleotide phosphodiesterase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0007165",
                "name": "signal transduction",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0008081",
                "name": "phosphoric diester hydrolase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "55c76fe585d3fb9c71ce12a59464e90a49687b13",
        "counters": {
            "domain_architectures": 20360,
            "entries": 14,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 1,
                "cathgene3d": 1,
                "ssf": 1,
                "smart": 1,
                "pfam": 1,
                "cdd": 1,
                "panther": 1,
                "prints": 1,
                "prosite": 1,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 20360
        }
    }
}