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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A2R6BHB0",
"id": "A0A2R6BHB0_9ARCH",
"source_organism": {
"taxId": "1978161",
"scientificName": "Candidatus Marsarchaeota G2 archaeon ECH_B_3",
"fullName": "Candidatus Marsarchaeota G2 archaeon ECH_B_3"
},
"name": "DNA polymerase beta",
"description": [
"Repair polymerase that plays a key role in base-excision repair. During this process, the damaged base is excised by specific DNA glycosylases, the DNA backbone is nicked at the abasic site by an apurinic/apyrimidic (AP) endonuclease, and POLB removes 5'-deoxyribose-phosphate from the preincised AP site acting as a 5'-deoxyribose-phosphate lyase (5'-dRP lyase); through its DNA polymerase activity, it adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. It is also able to cleave sugar-phosphate bonds 3' to an intact AP site, acting as an AP lyase"
],
"length": 564,
"sequence": "MDNQEIAGILEEYAELLELNGEDVFRVNAYRRAAKSLRNLNTDVVELWRSKRLKEVPGVGRAIAEKIDEIISTGRLRALEELRARIPSEVVELTGVPFVGPKTAKLLYTKFGVSSRAQLIEKLRDGSLVKQGFSPKLAEKILGAVEGVGEAFTKMLLIEGMNEASQLIDKIRGAEFELYVCGSIRRGKEAVGDVDVVVLSKTRDKTLLDLASKLRGGKTLAEGESKLTWVSLRGVQFDFRLAHPEYLGAMQLYFTGSKEHNIALRTHAQRLGFKLSEFGLFEQNGVRVAGASEEEVYSKLGLQYIEPELRENTGEIEAASKGVLPKLADASDVFGDYHVHSTWSDGVDTLERMVEGALRQGYKYVVFTDHSKSERVANGMSEERLRKQAEEIERLRSKYGSIEILHGSEVDILSGGRLDYDDRTLAQLDYVVASLHRRFTSDTEALTEAVIKALENRYVDTVGHPTNRMLGRRPENGVDLEKVLAAAKKNSKFLEVDGQPRRMDLPSIWVKRAVEEGVRLVLSSDAHSTAELGYMMFALINARRGWAAAQNIANSSHKFRSART",
"proteome": null,
"gene": "B9Q07_10875",
"go_terms": [
{
"identifier": "GO:0003677",
"name": "DNA binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0003887",
"name": "DNA-directed DNA polymerase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006281",
"name": "DNA repair",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0003824",
"name": "catalytic activity",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 4,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "b375f0577b909128d4198741efdb9feacb1f801f",
"counters": {
"domain_architectures": 441,
"entries": 38,
"isoforms": 0,
"proteomes": 0,
"sets": 5,
"structures": 0,
"taxa": 1,
"dbEntries": {
"pfam": 5,
"ssf": 3,
"cathgene3d": 5,
"smart": 3,
"cdd": 2,
"pirsf": 1,
"ncbifam": 1,
"panther": 1,
"prints": 1,
"interpro": 16
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 441
}
}
}