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{
    "metadata": {
        "accession": "A0A286XBS2",
        "id": "A0A286XBS2_CAVPO",
        "source_organism": {
            "taxId": "10141",
            "scientificName": "Cavia porcellus",
            "fullName": "Cavia porcellus (Guinea pig)"
        },
        "name": "E3 ubiquitin-protein ligase LNX",
        "description": [
            "E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65",
            "Isoform 2 provides an endocytic scaffold for IGSF5/JAM4"
        ],
        "length": 624,
        "sequence": "MKALLLLVLPWLSPANYIDNVGNLHFLYSELCKGASHYGLTKDRKRRSQDGSSDGCASLTATPLSPEVSEAPHEPGLDDPSCMSTVENCHPENSSSDTGRSNRTRAWPFERSSFRIRSFKKLNRAFSSLRRTKNGSIIANCADQSRENHENTTVPEVFPKFYHLIPRGEVTSIKINRVDPNESLSIRLVGGSETPLVHIIIQHIYSDGVIARDGRLLAGDIILKVNGMDISNVPHNYALNLLRKPCQVLWLTVLREKKFQSKRHAHSLYFCGPRNDSFQVILNKSSPEEQLGIKLVRKVDEPGVFVFSLLNGGVADRHGQLQENDRILAINGHDLRNGNPEIAALLIQASERRVHLVVSRQAREQSPVTCQEASRTHSSGQSPGPGDITPKPFCSAAVCHEKLVSVRKDPSESLGMTVAGGTSPREWDLPIYVISIEPGGIISRDGRIKTGDILLNVNGVELTGVTRSEAVALLKSSSSSVVLKALEVEEHVPQENCNGPEALDCIYNMSPPDVWSPSWVTWLELTQYLYNRKDVVLRRNIAGTLGFRIVGGYEENNGNKPFFIKSIVEGTPAYKDGRIRCGDILLAVNGRSTSGMMHAFLTRMLKEIKGRITLTIVSWPGTFL",
        "proteome": "UP000005447",
        "gene": "LNX1",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "3bb909df24b168eae25613c09d851f8b7fd7954b",
        "counters": {
            "domain_architectures": 3298,
            "entries": 13,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "cdd": 4,
                "profile": 1,
                "pfam": 1,
                "smart": 1,
                "panther": 1,
                "interpro": 3
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 3298
        }
    }
}