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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A286U7X0",
"id": "A0A286U7X0_9AGAM",
"source_organism": {
"taxId": "2282107",
"scientificName": "Pyrrhoderma noxium",
"fullName": "Pyrrhoderma noxium"
},
"name": "DNA polymerase beta",
"description": [
"Repair polymerase that plays a key role in base-excision repair. During this process, the damaged base is excised by specific DNA glycosylases, the DNA backbone is nicked at the abasic site by an apurinic/apyrimidic (AP) endonuclease, and POLB removes 5'-deoxyribose-phosphate from the preincised AP site acting as a 5'-deoxyribose-phosphate lyase (5'-dRP lyase); through its DNA polymerase activity, it adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. It is also able to cleave sugar-phosphate bonds 3' to an intact AP site, acting as an AP lyase"
],
"length": 833,
"sequence": "MNFVEKQRLLAGIPDEDFDEFRAQKRRRLQSEQKSSKLSTDSISISQSLVHPNLLSQQTEPEKSRNEPRSDSINAETNEQLQSLTGQASDDRQYSQPNPMEVDQSYQSSPKGRSLSRSISPPQPLLDTVSSDNILPSSLSRPEAKQQDEPSTISEPNSSNLRQNHGEASINNQQHDDVPQQSTENQDSEKMNTSIVTDITSPSNSPAVPLLRVTPRPRQTLESKRKMKAKKTSEMALKKKEEEEEKRMTPREYATKVQEKFKDELKKASEKELFLKNKTIFYVGGDYDKAVRSTRSRMDYLRKKGATVAPVYDPNTVTHIITDTNAKITLKALGLKSLDEIPFHIPTLRWTWISNRSDHHLFLHAAFAKRIDCGPEEVYPVPKRKKKDTRQAQDDWEFSRIEEFPTSLHEVPATNEGSSKTGQLIDVDLSTVAKKTADNDSTLHEFNIICDMVRGNQDLEFSDSAEENNVEGPSSLTDKAKPVFTCDRLNGDKKACPNQDVVDKLEALRKINEGKPSKQGDEQHWRLFSYGKSIAALKRYPKRIQSLEEAKSIKGVGEKTARKIMEIIRTGDLQRITYDNTEQVQVSNLFKGVYGVGSSTAYTWYSMGCRTLEDLEQRKGGVKLTDAQQIGLEHYEDINTRIPREEVTEIFNSIKKIALSIDPNLFVEVMGSYRRGKETCGDIDILMTRPTYDGRDHRGMLGILLKKLHEQKILTEDLAIPEDMEDLELTYRGLCRHGGNGRRRRIDILVIPWQYRGAALLYYTGDDIFNRAMRFKAKKMGYSLSQRGLSAGVLRNQRGKKLVPGKIIASETEEEIFRILDVPWQEPYERVRS",
"proteome": "UP000217199",
"gene": "PNOK_0851300",
"go_terms": [
{
"identifier": "GO:0003677",
"name": "DNA binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0003887",
"name": "DNA-directed DNA polymerase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006281",
"name": "DNA repair",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0034061",
"name": "DNA polymerase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0016779",
"name": "nucleotidyltransferase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "5fd7183be16cdf978797e5c747a48dff9c92f31e",
"counters": {
"domain_architectures": 4883,
"entries": 32,
"isoforms": 0,
"proteomes": 1,
"sets": 3,
"structures": 0,
"taxa": 1,
"dbEntries": {
"profile": 1,
"cathgene3d": 4,
"ssf": 3,
"pfam": 4,
"smart": 2,
"cdd": 1,
"panther": 1,
"prints": 2,
"prosite": 1,
"interpro": 13
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 4883
}
}
}