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{
"metadata": {
"accession": "A0A221NTI2",
"id": "A0A221NTI2_9ACTN",
"source_organism": {
"taxId": "1355015",
"scientificName": "Streptomyces pluripotens",
"fullName": "Streptomyces pluripotens"
},
"name": "Glutamate--cysteine ligase EgtA",
"description": [
"Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine"
],
"length": 450,
"sequence": "MSDTQSGGGDRIEHHTAVTEAEVDALVRGICFKTGPPRTLGVELEWLVHELRQPQLPVTPERLEAAYTALRAVPLGSALTVEPGGQLELSSPPAASLMECMGTVSADLESVRAVLAEDGLGLVGIGHDPWHTPHRFLREPRYDAMETCLDRTGPAGRHMMCATASVQVCVDAGHDGSGVFGHRRRWWLAHQLGAVLVAAFANSPLAGREPTGWMSTRQLRWTQIGAGRAGAPPLGGDPRSAWARHVLDSPVMCVRRDHGPWVVPDGLTFRQWARSRSPRPPTRADLDYHLTTLFPPIRPRGHLELRMIDAQPGEDGWIVPLAVTAALFDDPEATEAAYRSVKPLAERTLDLPAPHNPLWTGAARRGLADPDVREAATACFAAALRALPRLGATREVTDAVAAYRDRYVVRGRCPADDLLDGVRSTNRSPSRPGPTTGGTPVARGRKDIRT",
"proteome": "UP000031501",
"gene": "egtA",
"go_terms": [
{
"identifier": "GO:0003824",
"name": "catalytic activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0004357",
"name": "glutamate-cysteine ligase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006750",
"name": "glutathione biosynthetic process",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0052699",
"name": "ergothioneine biosynthetic process",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0042398",
"name": "modified amino acid biosynthetic process",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "173825e248e36dc994af2efdcb5f9e1f5a5931d5",
"counters": {
"domain_architectures": 26268,
"entries": 11,
"isoforms": 0,
"proteomes": 1,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"ssf": 1,
"pirsf": 1,
"hamap": 1,
"panther": 1,
"ncbifam": 1,
"pfam": 1,
"interpro": 4
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 26268
}
}
}