{"metadata":{"accession":"A0A221NTI2","id":"A0A221NTI2_9ACTN","source_organism":{"taxId":"1355015","scientificName":"Streptomyces pluripotens","fullName":"Streptomyces pluripotens"},"name":"Glutamate--cysteine ligase EgtA","description":["Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine"],"length":450,"sequence":"MSDTQSGGGDRIEHHTAVTEAEVDALVRGICFKTGPPRTLGVELEWLVHELRQPQLPVTPERLEAAYTALRAVPLGSALTVEPGGQLELSSPPAASLMECMGTVSADLESVRAVLAEDGLGLVGIGHDPWHTPHRFLREPRYDAMETCLDRTGPAGRHMMCATASVQVCVDAGHDGSGVFGHRRRWWLAHQLGAVLVAAFANSPLAGREPTGWMSTRQLRWTQIGAGRAGAPPLGGDPRSAWARHVLDSPVMCVRRDHGPWVVPDGLTFRQWARSRSPRPPTRADLDYHLTTLFPPIRPRGHLELRMIDAQPGEDGWIVPLAVTAALFDDPEATEAAYRSVKPLAERTLDLPAPHNPLWTGAARRGLADPDVREAATACFAAALRALPRLGATREVTDAVAAYRDRYVVRGRCPADDLLDGVRSTNRSPSRPGPTTGGTPVARGRKDIRT","proteome":"UP000031501","gene":"egtA","go_terms":[{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004357","name":"glutamate-cysteine ligase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006750","name":"glutathione biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0052699","name":"ergothioneine biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0042398","name":"modified amino acid biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"173825e248e36dc994af2efdcb5f9e1f5a5931d5","counters":{"domain_architectures":26268,"entries":11,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pirsf":1,"hamap":1,"panther":1,"ncbifam":1,"pfam":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":26268}}}