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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A1S3GRM8",
"id": "A0A1S3GRM8_DIPOR",
"source_organism": {
"taxId": "10020",
"scientificName": "Dipodomys ordii",
"fullName": "Dipodomys ordii (Ord's kangaroo rat)"
},
"name": "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial",
"description": [
"Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Electron transfer flavoprotein (ETF) is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Among the different mitochondrial acyl-CoA dehydrogenases, medium-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 6 to 12 carbons long primary chains"
],
"length": 421,
"sequence": "MAAAFRRSCRVLRSIAHFEWRSQHTQVSQKHEPGTGFSFELSEQQKEFQATARKFAREEIVPVAGEYDKSGEYPFPIIKRAWELGLINTHIPQSCGGLGLGTFDTCLITEELAYGCTGVQTAIEANSLGQMPVIIAGNDQQQKKYLGRLTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDDYIINGQKMWITNGGKASWYFLLARSDPDPKTPASKAFTGFIVEADSPGIQIGKKELNMGQRCSDTRGIVFEDVKVPKENVLIGEGAGFKIAMGAFDRTRPPVAAGAVGLAQRALDEATMYALERKTFGKLLVEHQGVSFLLAEMAMKVELARLSYQRAAWEVDAGRRNTYYASIAKAFAGDIANQLASDAVQIFGGYGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIIAREHISKYKK",
"proteome": "UP000081671",
"gene": "Acadm",
"go_terms": [
{
"identifier": "GO:0016627",
"name": "oxidoreductase activity, acting on the CH-CH group of donors",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0050660",
"name": "flavin adenine dinucleotide binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0070991",
"name": "medium-chain fatty acyl-CoA dehydrogenase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006635",
"name": "fatty acid beta-oxidation",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0005739",
"name": "mitochondrion",
"category": {
"code": "C",
"name": "cellular_component"
}
},
{
"identifier": "GO:0003995",
"name": "acyl-CoA dehydrogenase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "c9fd574aecd15169638af0612dc6d2bb4a1db62a",
"counters": {
"domain_architectures": 193077,
"entries": 22,
"isoforms": 0,
"proteomes": 1,
"sets": 3,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 3,
"ssf": 2,
"cdd": 1,
"pfam": 3,
"panther": 1,
"pirsf": 1,
"prosite": 2,
"interpro": 9
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 193077
}
}
}