{"metadata":{"accession":"A0A1S3GRM8","id":"A0A1S3GRM8_DIPOR","source_organism":{"taxId":"10020","scientificName":"Dipodomys ordii","fullName":"Dipodomys ordii (Ord's kangaroo rat)"},"name":"Medium-chain specific acyl-CoA dehydrogenase, mitochondrial","description":["Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Electron transfer flavoprotein (ETF) is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Among the different mitochondrial acyl-CoA dehydrogenases, medium-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 6 to 12 carbons long primary chains"],"length":421,"sequence":"MAAAFRRSCRVLRSIAHFEWRSQHTQVSQKHEPGTGFSFELSEQQKEFQATARKFAREEIVPVAGEYDKSGEYPFPIIKRAWELGLINTHIPQSCGGLGLGTFDTCLITEELAYGCTGVQTAIEANSLGQMPVIIAGNDQQQKKYLGRLTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDDYIINGQKMWITNGGKASWYFLLARSDPDPKTPASKAFTGFIVEADSPGIQIGKKELNMGQRCSDTRGIVFEDVKVPKENVLIGEGAGFKIAMGAFDRTRPPVAAGAVGLAQRALDEATMYALERKTFGKLLVEHQGVSFLLAEMAMKVELARLSYQRAAWEVDAGRRNTYYASIAKAFAGDIANQLASDAVQIFGGYGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIIAREHISKYKK","proteome":"UP000081671","gene":"Acadm","go_terms":[{"identifier":"GO:0016627","name":"oxidoreductase activity, acting on the CH-CH group of donors","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0050660","name":"flavin adenine dinucleotide binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0070991","name":"medium-chain fatty acyl-CoA dehydrogenase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006635","name":"fatty acid beta-oxidation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005739","name":"mitochondrion","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0003995","name":"acyl-CoA dehydrogenase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"c9fd574aecd15169638af0612dc6d2bb4a1db62a","counters":{"domain_architectures":193077,"entries":22,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":3,"ssf":2,"cdd":1,"pfam":3,"panther":1,"pirsf":1,"prosite":2,"interpro":9},"proteome":1,"taxonomy":1,"similar_proteins":193077}}}