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{
    "metadata": {
        "accession": "A0A091JE86",
        "id": "A0A091JE86_EGRGA",
        "source_organism": {
            "taxId": "188379",
            "scientificName": "Egretta garzetta",
            "fullName": "Egretta garzetta (Little egret)"
        },
        "name": "NADPH oxidase 2",
        "description": [
            "Catalytic subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). In the activated complex, electrons are first transferred from NADPH to flavin adenine dinucleotide (FAD) and subsequently transferred via two heme molecules to molecular oxygen, producing superoxide through an outer-sphere reaction. Activation of the NADPH oxidase complex is initiated by the assembly of cytosolic subunits of the NADPH oxidase complex with the core NADPH oxidase complex to form a complex at the plasma membrane or phagosomal membrane. This activation process is initiated by phosphorylation dependent binding of the cytosolic NCF1/p47-phox subunit to the C-terminus of CYBA/p22-phox. NADPH oxidase complex assembly is impaired through interaction with NRROS"
        ],
        "length": 570,
        "sequence": "MGNWVENEGLSIFVVLVWLGLNVFLFWWYYLVYDVPPKFFYTRVLLGRALALARAPAACLNFNCMLILLPVCRNLLSFLRGSSACCSTRVRRQLDRNLTFHKMVAWMIALHTAIHTIAHLFNVEWNVQARVEETRTLAAALSSLGDDPKQSYVNFYRNTIANPVGGLYVAFTYLAGLTGVIITLALILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLVIHGAGRIVRGQTAESLAEHNPEICYKNFSSWGSKGSCPIPQFSGNPPMTWKWVVGPMFLYLCERLVRLWRSQQKVVITKVVIHPFKTIELQMMKKGFKMEVGQYIFVKCPAVSKLEWHPFTLTSAPEEDYFSIHVRIVGDWTEGLFNACGCDKQEFQEAWKLPKIAVDGPFGTASEDVFSYETVMLVGAGIGVTPFASVLKSVWYKYCHDATNLKLKKIYFYWLCRDTHAFEWFADLLQSLEAQMQERNNADFLSYNIYLTGWDESQATHFVVHHEEEKDVITGLKQKTLYGRPNWENEFKTIAGKHPGSRIGVFLCGPEGLADTLNKQSISNSEADPRGVHFIFNKENF",
        "proteome": "UP000053119",
        "gene": "Z169_14677",
        "go_terms": [
            {
                "identifier": "GO:0016491",
                "name": "oxidoreductase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016020",
                "name": "membrane",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "496ce31aafc2f777618f119f81f7277d9a382e44",
        "counters": {
            "domain_architectures": 22735,
            "entries": 21,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 4,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "pfam": 3,
                "profile": 1,
                "cathgene3d": 2,
                "ssf": 2,
                "cdd": 1,
                "panther": 1,
                "sfld": 2,
                "prints": 1,
                "interpro": 8
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 22735
        }
    }
}