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{
    "metadata": {
        "accession": "PF23793",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR058979",
        "hierarchy": null,
        "name": {
            "name": "Rz1-like lysis system protein LysC",
            "short": "LysC"
        },
        "description": [
            {
                "text": "<p>This entry represents a group of proteins from tailed bacteriophages and bacterial prophages mainly found in proteobacteria, including LysC from Burkholderia phage ST79 (Bacteriophage ST79) ([swissprot:R4JDL9]). LysC is an Rz1-like component of a phage lytic system, substantially overlapping although not fully embedded in the gene for the Rz-like LysB component. The phage lysis defect in the absence of a functional LysB/LysC system appears in the presence of high concentrations of divalent cations [[cite:PUB00105751]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00105750": {
                "PMID": 17900620,
                "ISBN": null,
                "volume": "373",
                "issue": "5",
                "year": 2007,
                "title": "Rz/Rz1 lysis gene equivalents in phages of Gram-negative hosts.",
                "URL": null,
                "raw_pages": "1098-112",
                "medline_journal": "J Mol Biol",
                "ISO_journal": "J Mol Biol",
                "authors": [
                    "Summer EJ",
                    "Berry J",
                    "Tran TA",
                    "Niu L",
                    "Struck DK",
                    "Young R."
                ],
                "DOI_URL": null
            },
            "PUB00105751": {
                "PMID": 27038077,
                "ISBN": null,
                "volume": "121",
                "issue": "2",
                "year": 2016,
                "title": "Identification of the Burkholderia pseudomallei bacteriophage ST79 lysis gene cassette.",
                "URL": null,
                "raw_pages": "364-72",
                "medline_journal": "J Appl Microbiol",
                "ISO_journal": "J Appl Microbiol",
                "authors": [
                    "Khakhum N",
                    "Yordpratum U",
                    "Boonmee A",
                    "Tattawasart U",
                    "Rodrigues JL",
                    "Sermswan RW."
                ],
                "DOI_URL": null
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 5,
            "interactions": 0,
            "matches": 2072,
            "pathways": 0,
            "proteins": 2072,
            "proteomes": 557,
            "sets": 0,
            "structural_models": {
                "alphafold": 1556,
                "bfvd": 27
            },
            "structures": 0,
            "taxa": 1661
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 64,
            "alignment:full": 265
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}