{"metadata":{"accession":"PF23793","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR058979","hierarchy":null,"name":{"name":"Rz1-like lysis system protein LysC","short":"LysC"},"description":[{"text":"<p>This entry represents a group of proteins from tailed bacteriophages and bacterial prophages mainly found in proteobacteria, including LysC from Burkholderia phage ST79 (Bacteriophage ST79) ([swissprot:R4JDL9]). LysC is an Rz1-like component of a phage lytic system, substantially overlapping although not fully embedded in the gene for the Rz-like LysB component. The phage lysis defect in the absence of a functional LysB/LysC system appears in the presence of high concentrations of divalent cations [[cite:PUB00105751]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00105750":{"PMID":17900620,"ISBN":null,"volume":"373","issue":"5","year":2007,"title":"Rz/Rz1 lysis gene equivalents in phages of Gram-negative hosts.","URL":null,"raw_pages":"1098-112","medline_journal":"J Mol Biol","ISO_journal":"J Mol Biol","authors":["Summer EJ","Berry J","Tran TA","Niu L","Struck DK","Young R."],"DOI_URL":null},"PUB00105751":{"PMID":27038077,"ISBN":null,"volume":"121","issue":"2","year":2016,"title":"Identification of the Burkholderia pseudomallei bacteriophage ST79 lysis gene cassette.","URL":null,"raw_pages":"364-72","medline_journal":"J Appl Microbiol","ISO_journal":"J Appl Microbiol","authors":["Khakhum N","Yordpratum U","Boonmee A","Tattawasart U","Rodrigues JL","Sermswan RW."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":5,"interactions":0,"matches":2072,"pathways":0,"proteins":2072,"proteomes":557,"sets":0,"structural_models":{"alphafold":1556,"bfvd":27},"structures":0,"taxa":1661},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":64,"alignment:full":265},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}