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{
    "metadata": {
        "accession": "PF22758",
        "entry_id": null,
        "type": "family",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR054438",
        "hierarchy": null,
        "name": {
            "name": "Structural cement protein (E217 gp24/Pam3 gp6)",
            "short": "Phage_cement"
        },
        "description": [
            {
                "text": "<p>E217 is a Pseudomonas phage used in an experimental cocktail to eradicate cystic fibrosis-associated Pseudomonas aeruginosa. Gp24 is a trimeric structural protein and component of the E217 icosahedral head.Gp24 adopts a beta-tulip fold similar to the gp87 protein found in the thermophilic phage P74-26. Each gp24 subunit consists of two anti-parallel beta-sheets, that form a tulip-like structure. Gp24 structural protein probably stabilises the E217 capsid.  This entry includes the cement protein gp6 of cyanophage Pam3. It consists of an N-terminal beta-tulip domain followed by a C-terminal domain of seven antiparallel beta-strands. Gp6 trimers sit at the icosahedral threefold and quasi-threefold axes, stabilizing the capsid shell.</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00154413": {
                "PMID": 36656854,
                "ISBN": null,
                "volume": "120",
                "issue": "4",
                "year": 2023,
                "title": "Fine structure and assembly pattern of a minimal myophage Pam3.",
                "URL": null,
                "raw_pages": "e2213727120",
                "medline_journal": "Proc Natl Acad Sci U S A",
                "ISO_journal": "Proc Natl Acad Sci U S A",
                "authors": [
                    "Yang F",
                    "Jiang YL",
                    "Zhang JT",
                    "Zhu J",
                    "Du K",
                    "Yu RC",
                    "Wei ZL",
                    "Kong WW",
                    "Cui N",
                    "Li WF",
                    "Chen Y",
                    "Li Q",
                    "Zhou CZ."
                ],
                "DOI_URL": "https://doi.org/10.1073/pnas.2213727120"
            },
            "PUB00153918": {
                "PMID": 37422479,
                "ISBN": null,
                "volume": "14",
                "issue": "1",
                "year": 2023,
                "title": "High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217.",
                "URL": null,
                "raw_pages": "4052",
                "medline_journal": "Nat Commun",
                "ISO_journal": "Nat Commun",
                "authors": [
                    "Li F",
                    "Hou CD",
                    "Lokareddy RK",
                    "Yang R",
                    "Forti F",
                    "Briani F",
                    "Cingolani G."
                ],
                "DOI_URL": "https://doi.org/10.1038/s41467-023-39756-z"
            }
        },
        "set_info": {
            "accession": "CL0845",
            "name": "Beta_tulip"
        },
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 7,
            "interactions": 0,
            "matches": 1250,
            "pathways": 0,
            "proteins": 1246,
            "proteomes": 639,
            "sets": 1,
            "structural_models": {
                "alphafold": 598,
                "bfvd": 15
            },
            "structures": 6,
            "taxa": 2060
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 161,
            "alignment:full": 368
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}