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{
"metadata": {
"accession": "PF18504",
"entry_id": null,
"type": "coiled_coil",
"go_terms": null,
"source_database": "pfam",
"member_databases": null,
"integrated": "IPR041671",
"hierarchy": null,
"name": {
"name": "Csm1 N-terminal domain",
"short": "Csm1_N"
},
"description": [
{
"text": "<p>In the budding yeast Saccharomyces cerevisiae, sister chromatid co-orientation in meiosis I depends on the four-protein monopolin complex (Mam1, Csm1, Lrs4, and Hrr25/casein kinase 1), which localizes to centromeres from meiotic prophase through metaphase I. Csm1 and Lrs4, form a complex that resides in the nucleolus during interphase and relocalizes to centromeres during meiotic prophase, accompanied by phosphorylation of Lrs4. This is the N-terminal domain of Csm1 which forms a coiled-coil [[cite:PUB00054045]].</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": {
"PUB00054045": {
"PMID": 20723757,
"ISBN": null,
"volume": "142",
"issue": "4",
"year": 2010,
"title": "The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments.",
"URL": null,
"raw_pages": "556-67",
"medline_journal": "Cell",
"ISO_journal": "Cell",
"authors": [
"Corbett KD",
"Yip CK",
"Ee LS",
"Walz T",
"Amon A",
"Harrison SC."
],
"DOI_URL": "http://dx.doi.org/10.1016/j.cell.2010.07.017"
}
},
"set_info": null,
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"counters": {
"subfamilies": 0,
"domain_architectures": 5,
"interactions": 0,
"matches": 75,
"pathways": 0,
"proteins": 75,
"proteomes": 57,
"sets": 0,
"structural_models": {
"alphafold": 69,
"bfvd": 0
},
"structures": 3,
"taxa": 218
},
"entry_annotations": {
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"alignment:seed": 13,
"alignment:full": 29
},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": null
}
}