{"metadata":{"accession":"PF18504","entry_id":null,"type":"coiled_coil","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR041671","hierarchy":null,"name":{"name":"Csm1 N-terminal domain","short":"Csm1_N"},"description":[{"text":"<p>In the budding yeast Saccharomyces cerevisiae, sister chromatid co-orientation in meiosis I depends on the four-protein monopolin complex (Mam1, Csm1, Lrs4, and Hrr25/casein kinase 1), which localizes to centromeres from meiotic prophase through metaphase I. Csm1 and Lrs4, form a complex that resides in the nucleolus during interphase and relocalizes to centromeres during meiotic prophase, accompanied by phosphorylation of Lrs4. This is the N-terminal domain of Csm1 which forms a coiled-coil [[cite:PUB00054045]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00054045":{"PMID":20723757,"ISBN":null,"volume":"142","issue":"4","year":2010,"title":"The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments.","URL":null,"raw_pages":"556-67","medline_journal":"Cell","ISO_journal":"Cell","authors":["Corbett KD","Yip CK","Ee LS","Walz T","Amon A","Harrison SC."],"DOI_URL":"http://dx.doi.org/10.1016/j.cell.2010.07.017"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":5,"interactions":0,"matches":75,"pathways":0,"proteins":75,"proteomes":57,"sets":0,"structural_models":{"alphafold":69,"bfvd":0},"structures":3,"taxa":218},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":13,"alignment:full":29},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}