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{
    "metadata": {
        "accession": "PF14662",
        "entry_id": null,
        "type": "coiled_coil",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR028168",
        "hierarchy": null,
        "name": {
            "name": "Coiled-coil region of CCDC155 or KASH",
            "short": "KASH_CCD"
        },
        "description": [
            {
                "text": "<p>This coiled-coil region is found in the central part of KASH or Klarsicht/ANC-1/Syne/homology proteins. KASH are a meiosis-specific proteins that localise at telomeres and interact with SUN1, thus being implicated in meiotic chromosome dynamics and homologue pairing [[cite:PUB00067615]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00067615": {
                "PMID": 22826121,
                "ISBN": null,
                "volume": "198",
                "issue": "2",
                "year": 2012,
                "title": "A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.",
                "URL": null,
                "raw_pages": "165-72",
                "medline_journal": "J Cell Biol",
                "ISO_journal": "J. Cell Biol.",
                "authors": [
                    "Morimoto A",
                    "Shibuya H",
                    "Zhu X",
                    "Kim J",
                    "Ishiguro K",
                    "Han M",
                    "Watanabe Y."
                ],
                "DOI_URL": "http://dx.doi.org/10.1083/jcb.201204085"
            }
        },
        "set_info": null,
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 25,
            "interactions": 0,
            "matches": 1679,
            "pathways": 0,
            "proteins": 1629,
            "proteomes": 655,
            "sets": 0,
            "structural_models": {
                "alphafold": 979,
                "bfvd": 0
            },
            "structures": 0,
            "taxa": 2176
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 7,
            "alignment:full": 1192
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}