{"metadata":{"accession":"PF14662","entry_id":null,"type":"coiled_coil","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR028168","hierarchy":null,"name":{"name":"Coiled-coil region of CCDC155 or KASH","short":"KASH_CCD"},"description":[{"text":"<p>This coiled-coil region is found in the central part of KASH or Klarsicht/ANC-1/Syne/homology proteins. KASH are a meiosis-specific proteins that localise at telomeres and interact with SUN1, thus being implicated in meiotic chromosome dynamics and homologue pairing [[cite:PUB00067615]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00067615":{"PMID":22826121,"ISBN":null,"volume":"198","issue":"2","year":2012,"title":"A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.","URL":null,"raw_pages":"165-72","medline_journal":"J Cell Biol","ISO_journal":"J. Cell Biol.","authors":["Morimoto A","Shibuya H","Zhu X","Kim J","Ishiguro K","Han M","Watanabe Y."],"DOI_URL":"http://dx.doi.org/10.1083/jcb.201204085"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":25,"interactions":0,"matches":1679,"pathways":0,"proteins":1629,"proteomes":655,"sets":0,"structural_models":{"alphafold":979,"bfvd":0},"structures":0,"taxa":2176},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":7,"alignment:full":1192},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}