General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "PF13337",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR014061",
        "hierarchy": null,
        "name": {
            "name": "Lon-like protease BrxL-like, ATPase domain",
            "short": "BrxL_ATPase"
        },
        "description": [
            {
                "text": "<p>This entry represents the ATPase domain found in BREX system Lon protease-like protein BrxL from Bacillus cereus and similar proteins. BrxL is part of a type 1 BREX system which contains a C-terminal Lon-like protease domain ([pfam:PF05362]. BREX systems (bacteriophage exclusion) provide immunity against bacteriophage, a system that allows phage adsorption but prevents phage DNA replication, without degradation of the phage DNA [[cite:PUB00093365]]. Methylation of bacterial DNA by PglX probably guides self/non-self discrimination. This entry also includes a few uncharacterised viral sequences.</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00093365": {
                "PMID": 25452498,
                "ISBN": null,
                "volume": "34",
                "issue": "2",
                "year": 2015,
                "title": "BREX is a novel phage resistance system widespread in microbial genomes.",
                "URL": null,
                "raw_pages": "169-83",
                "medline_journal": "EMBO J",
                "ISO_journal": "EMBO J.",
                "authors": [
                    "Goldfarb T",
                    "Sberro H",
                    "Weinstock E",
                    "Cohen O",
                    "Doron S",
                    "Charpak-Amikam Y",
                    "Afik S",
                    "Ofir G",
                    "Sorek R."
                ],
                "DOI_URL": null
            }
        },
        "set_info": {
            "accession": "CL0023",
            "name": "P-loop_NTPase"
        },
        "overlaps_with": null,
        "counters": {
            "subfamilies": 0,
            "domain_architectures": 16,
            "interactions": 0,
            "matches": 2169,
            "pathways": 0,
            "proteins": 2168,
            "proteomes": 1189,
            "sets": 1,
            "structural_models": {
                "alphafold": 1751,
                "bfvd": 2
            },
            "structures": 2,
            "taxa": 3559
        },
        "entry_annotations": {
            "hmm": 0,
            "logo": 0,
            "alignment:seed": 38,
            "alignment:full": 744
        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}